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TDF therapy in pregnancy reduces HBV DNA, risk of vertical transmission

August 3, 2015

Viremic mothers treated with tenofovir disoproxil fumarate during pregnancy had decreased hepatitis B virus infection DNA levels in their blood, which reduced the infection’s DNA serum levels in infants at birth and reduced overall mother-to-child transmission, according to study data.

“We conducted this clinical trial with the aims of evaluating the efficacy of [tenofovir disoproxil fumarate] administration initiated at 30 [to] 32 weeks of gestation in highly viremic pregnant mothers, assessing the efficacy in reducing mother-to-infant HBV transmission, and monitoring safety for the mothers and infants during pregnancy and the postpartum period,” the researchers wrote.

In the Journals

Adolescents see improved mental health after bariatric surgery

August 3, 2015
Following bariatric surgery, most teens with severe obesity experience improved mental health; however, one in five continues to experience symptoms of depression…
Kathryn Edwards In the Journals

P1 type 1 genotype, MLVA type 4/5/7/2 predominate CAP cases

August 3, 2015
Among patients hospitalized with community-acquired pneumonia, the P1 type 1 genotype and MLVA type 4/5/7/2 were the most prevalent, but the proportion of these types…

BLOG: Patient financing also can be used as a marketing tool

August 3, 2015
I speak with health care practices on a regular basis. During these conversations, physicians usually ask a range of questions to help determine whether they should…
In the Journals

Stool samples offer noninvasive diagnostics for parechovirus in children

August 3, 2015
The use of noninvasive PCR-based human parechovirus diagnostics from stool samples of pediatric patients improved the accuracy of hospital-based central nervous system…
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Pediatric Acute Lymphoblastic Leukemia: From Diagnosis to Prognosis

Pediatric Annals, July 2015, Volume 44 Issue 7
Pediatric acute lymphoblastic leukemia is the most common childhood cancer. Although the appearance of the disease is…
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Pediatric Annals April 2015

Vaccines: April 2015

Keck School of Medicine of USC and Pediatric Annals

Vaccine refusal and hesitancy to vaccinatehas been a growing problem in the past 2-3decades. Perhaps victims of our…
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Meeting News Coverage Video
New mothers preferred to receive vaccine information from pediatrician vs. obstetrician

New mothers preferred to receive vaccine information from pediatrician vs. obstetrician

May 12, 2015
SAN DIEGO — Sean O’Leary, MD, MPH, from the department of pediatrics at the University of Colorado…
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