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FDA to review pediatric hexavalent vaccine

October 21, 2014

The FDA has accepted for review a Biologics License Application filed by Merck and Sanofi Pasteur for a pediatric hexavalent combination vaccine containing DTaP, inactivated poliovirus, Haemophilus influenzae type B and hepatitis B vaccines, according to a company press release.

The application acceptance is based on phase 3 study data, presented at IDWeek 2014 in Philadelphia, which indicated vaccine safety and immunogenicity among infants.

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NIH awards seven research grants for vaccine adjuvants

October 18, 2014
The National Institute of Allergy and Infectious Diseases, a division of the NIH, has awarded seven research grants to separate institutions to explore and develop new…

$5.8 million contract awarded for development of third Ebola vaccine

October 17, 2014
The US Department of Health and Human Services announced a $5.8 million contract toward the development of a third Ebola vaccine, according to a press release.The…
In the Journals

Vaccination coverage rates high among US kindergarteners

October 16, 2014
Routine vaccination coverage among children in kindergarten was at or near the 95% national Healthy People 2020 target for DTaP, measles-mumps-rubella and…
Trend Watch

Trend Watch

Pediatric Annals, December 2012, Volume 41 Issue 12
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Immunization An Update

Keck School of Medicine of USC and Pediatric Annals

In the current environment of increasing vaccine refusal, the pediatrician has a powerful role to play as a trusted…
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In the Journals

Two doses of varicella vaccine more effective than one

June 23, 2014
A two dose regimen of varicella vaccine provided more protection than a one dose regimen among school-aged children, according to study findings in…
Healthy Baby

The Vicar of Vicarious Vaccine-Preventable Diseases

Pediatric Annals, June 2014, Volume 43 Issue 6
Perspective

Pertussis cases reach epidemic proportions in California

June 17, 2014
California has reported more than 800 cases of pertussis in the past 2 weeks, and the number of cases has reached epidemic proportions, according to…
In the Journals Perspective

Seizures, skin lesions common indicators of HSV in infants

June 16, 2014
Physicians should consider herpes simplex virus meningoencephalitis among infants aged younger than 3 months, especially if infants experience…
In the Journals

WHO: Two doses of measles vaccine needed in eastern Mediterranean region

June 13, 2014
To achieve measles elimination in the eastern Mediterranean region, an increase in second-dose vaccination is needed, particularly in countries with…

CDC: Progress made in global polio eradication since 2012

June 10, 2014
In the past 2 years, there has been significant progress toward polio eradication despite an upsurge of cases in 2013, according to a report in…
In the Journals

MMRV vaccine increased risk for febrile seizures

June 10, 2014
Canadian children who received the combination measles-mumps-rubella-varicella vaccine were at twice the risk for febrile seizures compared with…
In the Journals Perspective

Varicella incidence rates decrease while vaccination rates increase

June 9, 2014
Varicella incidence and hospitalization rates have decreased among children since the introduction of varicella vaccine 15 years ago, according to…
In the Journals Perspective

IPD, pneumonia rates remain high among children with chronic conditions

June 5, 2014
Despite widespread use of 7-valent pneumococcal conjugate vaccine and an overall decline in rates of invasive pneumococcal disease, pneumonia, and…
In the Journals

Rotavirus infection uncommon in Nicaragua after routine rotavirus vaccination

June 5, 2014
Following the introduction of the pentavalent rotavirus vaccine in Leon, Nicaragua, rotavirus was not commonly detected among children with diarrhea…
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