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Recurrent invasive pneumococcal disease predicts pediatric primary immune deficiencies

April 17, 2015

Recurrent invasive pneumococcal disease episodes are a significant indicator for the presence of primary immune deficiencies in children, according to results of a 29-year Danish study.

“Recurrent invasive pneumococcal disease occurs mostly in children with an underlying disease, but some cases remain unexplained,” Helene Ingels, MD, of the National Neisseria and Streptococcus Reference Center and the department of microbiological surveillance and research at the Statens Serum Institut in Denmark, and colleagues wrote. “Immunodeficiency has been described in [these children] but the prevalence is unknown.”

In the Journals

N. lactamica may suppress meningococcal outbreaks

April 16, 2015
Nasal inoculation with live Neisseria lactamica inhibited meningococcal carriage in young adults, according to results of a block-randomized human challenge…
VIDEO: Too soon to encourage vaccination in US by withholding state assistance Meeting News CoverageVideo

VIDEO: Too soon to encourage vaccination in US by withholding state assistance

April 15, 2015
BETHESDA, Md. — Walter A. Orenstein, MD, professor of medicine and associate director of the Emory Vaccine Center at Emory University School of Medicine, discusses…
In the Journals

Rotavirus vaccination sustains herd immunity in US

April 15, 2015
Data suggest a significant and sustained decrease in the incidence for seasonal rotavirus activity as well as evidence of herd immunity years after the introduction of…
CME CME

Vaccine-Preventable Outbreaks: Still with Us After All These Years

Pediatric Annals, April 2015, Volume 44 Issue 4
Outbreaks of vaccine-preventable diseases continue to occur in the United States, and they have been occurring at…
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CME

Immunization An Update

Keck School of Medicine of USC and Pediatric Annals

In the current environment of increasing vaccine refusal, the pediatrician has a powerful role to play as a trusted…
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Video: Paul A. Offit, MD, discusses religious exemptions from important vaccinations

February 11, 2015
Paul A. Offit, MD, chief of the division of infectious diseases at The Children’s Hospital of Philadelphia…
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CDC: Severe flu season continues; antivirals underused

January 9, 2015
Approximately halfway through the season, influenza remains severe but antiviral drugs are significantly underused despite their proven benefit on…

WHO approves meningitis A vaccine for infants in sub-Saharan Africa

January 8, 2015
WHO has approved an affordable meningitis A vaccine for infants in Africa, allowing for routine immunization of millions of additional people in a…
Ashleigh McGirr, MPH In the Journals

Earlier booster vaccination may be required after DTaP

January 7, 2015
Earlier booster vaccination and repeated boosting strategies for DTaP may be necessary to achieve herd immunity, according to meta-analysis data that…
Nicola P. Klein, MD, PhD In the Journals

MMRV showed higher risk for febrile seizures vs. MMR, varicella

January 6, 2015
Measles-mumps-rubella-varicella vaccine and measles-mumps-rubella and varicella vaccines had comparable risk for numerous adverse events, although…
Daniel M. Weinberger, PhD In the Journals

RSV may increase risk for bacterial pneumonia in infants

January 6, 2015
New study results published in PLOS Medicine suggest respiratory syncytial virus may increase the risk for pneumococcal pneumonia in…

CDC: Aseptic meningitis outbreak among football players linked to echovirus 30

December 31, 2014
Laboratory testing indicated an association between echovirus 30 and an outbreak of aseptic meningitis among high school football players in…

Influenza in US hits epidemic threshold

December 31, 2014
Influenza activity in the United States has reached an epidemic level for the 2014-2015 season, with national incidence of influenza-like illness…
Melissa Stockwell In the Journals

Electronic reminder increased influenza vaccination rates in late winter

December 31, 2014
Study findings indicated that an electronic vaccination reminder that utilized immunization information from a population-based system increased…
Melissa Stockwell In the Journals

Inclusion of vaccine education improved efficacy of text message reminders

December 30, 2014
Embedding vaccine education information within text message vaccine reminders significantly improved timely receipt of a second dose of influenza…
In the Journals

California pertussis epidemic cases reach near 70-year high

December 29, 2014
There have been 9,935 reported cases of pertussis within the current epidemic in California, representing the state’s greatest number of…
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