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FDA to review pediatric hexavalent vaccine

October 21, 2014

The FDA has accepted for review a Biologics License Application filed by Merck and Sanofi Pasteur for a pediatric hexavalent combination vaccine containing DTaP, inactivated poliovirus, Haemophilus influenzae type B and hepatitis B vaccines, according to a company press release.

The application acceptance is based on phase 3 study data, presented at IDWeek 2014 in Philadelphia, which indicated vaccine safety and immunogenicity among infants.

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NIH awards seven research grants for vaccine adjuvants

October 18, 2014
The National Institute of Allergy and Infectious Diseases, a division of the NIH, has awarded seven research grants to separate institutions to explore and develop new…

$5.8 million contract awarded for development of third Ebola vaccine

October 17, 2014
The US Department of Health and Human Services announced a $5.8 million contract toward the development of a third Ebola vaccine, according to a press release.The…
In the Journals

Vaccination coverage rates high among US kindergarteners

October 16, 2014
Routine vaccination coverage among children in kindergarten was at or near the 95% national Healthy People 2020 target for DTaP, measles-mumps-rubella and…
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Trend Watch

Pediatric Annals, December 2012, Volume 41 Issue 12
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Immunization An Update

Keck School of Medicine of USC and Pediatric Annals

In the current environment of increasing vaccine refusal, the pediatrician has a powerful role to play as a trusted…
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In the Journals

Webinar, in-person consultations increased pediatric vaccination coverage

July 7, 2014
Webinar consultations of the CDC’s Assessment, Feedback, Incentives, and eXchange program were just as effective as in-person consultations in…
In the Journals

Greater abundance of stool microbiota linked to higher vaccine response in infants

July 7, 2014
A significant abundance of stool Actinobacteria, particularly Bifidobacterium, was tied to higher responses to oral and parenteral vaccines and a…

Effective surveillance led to control of 2013 cholera outbreak in Mexico

July 7, 2014
Ongoing microbiologic surveillance of Vibrio cholerae infection in Mexico successfully controlled an outbreak in the La Huasteca region within 13…
In the Journals

Vaccine transparency can increase confidence, immunization rates

July 3, 2014
Despite the public health triumphs of vaccines, the number of parents who hesitate to immunize their children is increasing, according to a…
In the Journals

Adjuvanted HPV vaccine promoted long-term antibody persistence in preteen, adolescent girls

July 3, 2014
Data from an ongoing study indicate that the bivalent HPV vaccine induced high anti-HPV antibody levels up to 6 years after vaccination, which were…
In the Journals

Most shigellosis cases caused by S. flexneri, S. sonnei

July 2, 2014
Data from the Global Enteric Multicenter Study suggest that a vaccine for Shigella must protect against S. sonnei and 15 serotypes of S.
In the Journals

Routine vaccines rarely associated with adverse events in children

July 1, 2014
Recent data show that some vaccines recommended for routine use in children are associated with adverse events. However, these events are rare and…
In the Journals

AAP releases non-viral STI screening recommendations

July 1, 2014
The AAP’s Committee on Adolescence and Society for Adolescent Health and Medicine published recommendations on screening adolescents for…
In the Journals

HCPs have significant role in prevention of health care-associated pertussis

June 30, 2014
Health care professionals should take advantage of their significant role in the prevention of health care-associated pertussis, as the country…
In the Journals

Tdap vaccines showed waning efficacy during 2012 pertussis outbreak

June 30, 2014
During a 2012 outbreak of pertussis in Wisconsin, inoculation of adolescents with Tdap vaccinations showed dwindling immunity with time, according to…
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