Vaccine-Preventable Diseases

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Bexsero vaccine booster effective for waning immunity

February 9, 2016

Recent findings in a phase 2b trial showed that a booster dose for the three-dose serogroup B meningococcal vaccine can overcome waning immunity after early infant immunization, and administration of the booster at 12 months could help maintain immunity.

“This study of over 1,500 participants provides novel data on the persistence through the second year of life of bactericidal antibody induced by various infant 4CMenB immunization regimens and on the immunogenicity and reactogenicity profile of 4CMenB given as two doses in the second year of life,” Matthew D. Snape, MD, of the department of pediatrics at the University of Oxford, and colleagues wrote. “These data, combined with local age-specific epidemiology, are vital for the design of the optimal strategies for implementation of 4CMenB immunization programs.”

In the Journals

Oregon teen’s death linked to rare measles complication

February 8, 2016
The Oregon Health Authority reported that the 2015 death of a boy aged 14 years was the result of subacute sclerosing panencephalitis, a rare but fatal complication of…
In the Journals

Rapidly waning Tdap offers little long-term protection against pertussis

February 5, 2016
Tdap vaccine waned rapidly and provided only limited, short-term protection against pertussis when administered to adolescents as a booster for DTaP, according to recent…

Chickenpox, shingles vaccine associated with corneal inflammation

February 4, 2016
Analysis of case reports identified an association between the varicella zoster vaccine and keratitis in both children and adults, according to recently presented…
CME Article

Navigating Parental Vaccine Hesitancy

Pediatric Annals, August 2010, Volume 39 Issue 8
Pediatricians routinely encounter families who question the safety and necessity of childhood immunizations. Responding…
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Operation Immunization 2016: Enhancing HPV Immunization

This activity is supported by an educational grant from Merck & Co. Inc.

During the last decade, several new vaccines, including the meningococcal conjugate (MCV4), tetanus, diphtheria…
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Meeting News CoverageVideo

Recommendation challenges persist for HPV, influenza, meningoccocal vaccines

November 21, 2015
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In the Journals

Twenty percent of pediatricians dismiss families who refuse vaccines

November 4, 2015
A significant portion of pediatricians reported that they often or always dismiss families if parents refuse to have their children vaccinated…
In the Journals

Genetically engineered RSV vaccine shows early promise

November 4, 2015
A live-attenuated respiratory syncytial virus vaccine candidate lacking a specific protein may decrease viral replication while inducing a protective…
In the Journals

Less than 15% of adolescent boys complete HPV vaccination

November 4, 2015
In 2013, approximately two-thirds of boys aged 13 to 17 years had not received the HPV vaccination, according to recently published data in…

Daiichi Sankyo recalls two measles-containing vaccines

November 3, 2015
Daiichi Sankyo, a Japanese-based pharmaceuticals company, issued a voluntary recall for two of its vaccine products, according to a press release.The…
Meeting News Coverage

Compliance with Pneumovax 23 vaccination poor among high-risk patients

October 30, 2015
WASHINGTON — High-risk patients demonstrated poor overall compliance rates with Pneumovax 23 vaccination, varying widely across diagnoses…
Meeting News Coverage

Investigational hexavalent vaccine safe, effective when given with RotaTeq, Prevnar 13

October 28, 2015
WASHINGTON — An investigational combination hexavalent vaccine for protection against diphtheria, tetanus, pertussis, poliovirus, Haemophilus
In the Journals

AAP statement cites dangers of global warming on pediatric health

October 26, 2015
WASHINGTON — Global climate change has a direct impact on the health of children worldwide — adding risks such as heat stress, diminished…
In the Journals

RTS,S/AS01-induced antibody titers predict long-term vaccine efficacy

October 22, 2015
Antibody titers generated from RTS,S/AS01, a malaria vaccine that targets Plasmodium falciparum circumsporozoite protein, predicted the efficacy of…

ACIP approves updates to 2016 child, adolescent immunization schedule

October 21, 2015
The CDC’s Advisory Committee on Immunization Practices voted unanimously today to approve various updates to the 2016 child and adolescent…
In the Journals

Infant vaccine schedule with bOPV noninferior to IPV

October 19, 2015
Sequential schedules of inactivated poliovirus vaccines and bivalent oral poliovirus vaccines appeared to be noninferior compared with an inactivated…
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