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Recurrent invasive pneumococcal disease predicts pediatric primary immune deficiencies

April 17, 2015

Recurrent invasive pneumococcal disease episodes are a significant indicator for the presence of primary immune deficiencies in children, according to results of a 29-year Danish study.

“Recurrent invasive pneumococcal disease occurs mostly in children with an underlying disease, but some cases remain unexplained,” Helene Ingels, MD, of the National Neisseria and Streptococcus Reference Center and the department of microbiological surveillance and research at the Statens Serum Institut in Denmark, and colleagues wrote. “Immunodeficiency has been described in [these children] but the prevalence is unknown.”

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