Vaccine-Preventable Diseases

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Rapidly waning Tdap offers little long-term protection against pertussis

Rapidly waning Tdap offers little long-term protection against pertussis
February 5, 2016

Tdap vaccine waned rapidly and provided only limited, short-term protection against pertussis when administered to adolescents as a booster for DTaP, according to recent research in Pediatrics.

“This study investigated the effectiveness of Tdap against pertussis in a highly vaccinated population during two successive epidemics,” Nicola P. Klein, MD, PhD, of the Northern California Kaiser Permanente Vaccine Study Center, and colleagues wrote. “We demonstrate that among a cohort of teenagers who have exclusively received acellular pertussis vaccines, Tdap provides moderate protection 1 year after vaccination and then protection wanes rapidly.”

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Adolescent Immunization: 2015 and Beyond

Pediatric Annals, April 2015, Volume 44 Issue 4
In the last decade, the approach to adolescent immunizations has changed substantially. At ages 11 or 12 years, routine…
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This activity is supported by an educational grant from Merck & Co. Inc.

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