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FDA to review pediatric hexavalent vaccine

October 21, 2014

The FDA has accepted for review a Biologics License Application filed by Merck and Sanofi Pasteur for a pediatric hexavalent combination vaccine containing DTaP, inactivated poliovirus, Haemophilus influenzae type B and hepatitis B vaccines, according to a company press release.

The application acceptance is based on phase 3 study data, presented at IDWeek 2014 in Philadelphia, which indicated vaccine safety and immunogenicity among infants.

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NIH awards seven research grants for vaccine adjuvants

October 18, 2014
The National Institute of Allergy and Infectious Diseases, a division of the NIH, has awarded seven research grants to separate institutions to explore and develop new…

$5.8 million contract awarded for development of third Ebola vaccine

October 17, 2014
The US Department of Health and Human Services announced a $5.8 million contract toward the development of a third Ebola vaccine, according to a press release.The…
In the Journals

Vaccination coverage rates high among US kindergarteners

October 16, 2014
Routine vaccination coverage among children in kindergarten was at or near the 95% national Healthy People 2020 target for DTaP, measles-mumps-rubella and…
Healthy Baby

The Vicar of Vicarious Vaccine-Preventable Diseases

Pediatric Annals, June 2014, Volume 43 Issue 6
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CME
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Immunization An Update

Keck School of Medicine of USC and Pediatric Annals

In the current environment of increasing vaccine refusal, the pediatrician has a powerful role to play as a trusted…
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In the Journals

Hypertension-associated mortality high among infants with congenital rubella syndrome

July 25, 2014
Infants with congenital rubella syndrome had a high pulmonary hypertension-associated mortality rate, according to study findings in…
In the Journals

CDC: HPV vaccination rates unsatisfactory among teens

July 24, 2014
HPV vaccination coverage is unacceptably low among adolescents, despite a slight increase in coverage since 2012, according to data presented in a…
In the Journals

MenACWY-CRM booster dose elicited robust immune response

July 18, 2014
Recent data show children who received a booster dose of MenACWY-CRM following primary immunization with either MenACWY-CRM-D or MenACWY-D had strong…
In the Journals

Poverty, poor health, exposure are risk factors for IPD among South African children

July 16, 2014
Recent data shows previously identified risk factors related to poverty, poor health, and intense exposure continue to be risk factors for invasive…
In the Journals

IPV improved intestinal immunity among children given OPV

July 15, 2014
An additional dose of inactivated poliovirus vaccine increased intestinal immunity among children who previously received oral poliovirus vaccine and…
In the Journals

Dengue vaccine efficacious in phase 3 trial

July 15, 2014
Sanofi Pasteur’s investigational quadrivalent dengue vaccine demonstrated an overall efficacy of 56.5% and led to an 88.5% reduction of severe…
In the Journals

Congress called to address health, safety of illegal immigrants

July 9, 2014
The Association of American Physicians and Surgeons has sent an open letter to Congress, requesting they address the health and safety of illegal…
In the Journals

Children with comorbidities more likely to have non-vaccine serotype IPD

July 8, 2014
Non-vaccine serotypes of invasive pneumococcal disease are more common among children with underlying conditions, according to study findings in…
In the Journals

HPV vaccination not linked to VTE

July 8, 2014
Quadrivalent HPV vaccination was not associated with increased risk for venous thromboembolism, according to results of a self-controlled case-series…

CDC offers interim guidance on polio vaccination for travel

July 8, 2014
The CDC is advising physicians of interim travel recommendations regarding polio vaccination, according to an MMWR report. The guidance was issued…
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