March 28, 2017
Three doses of a live, low-cost and heat-stable oral bovine rotavirus pentavalent vaccine could prevent cases of severe rotavirus gastroenteritis in 66.7% of children in Niger, according to a recent study published in The New England Journal of Medicine.
“Sub-Saharan Africa has the highest rate of death associated with rotavirus disease, but vaccination on a large scale presents challenges,” Sheila Isanaka, ScD, assistant professor of nutrition within the department of global health and population, T.H. Chan School of Public Health, Harvard University, and colleagues wrote. “Current prices of the two licensed vaccines [used by WHO] are probably unsustainable without external subsidies. In addition, the global supply of the vaccines is constrained, and unreliable transportation and storage systems make delivery of vaccines that require refrigeration difficult.”