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Genetic, structural defects triggered epileptic seizures after vaccination

September 17, 2014

Read the Perspective from Paul A. Offit, MD

Recent data show that genetic or structural defects were the common underlying cause of epilepsy onset after routine vaccination.

Nienke E. Verbeek, MD, MSc, of the University Medical Centre Utrecht in the Netherlands, and colleagues reviewed data from the National Institute for Public Health and Environment in the Netherlands for 990 children who experienced seizures after vaccination during the first 2 years of life. Of these, 26 children were subsequently diagnosed with epilepsy and had seizure onset within 24 hours after inactivated vaccine administration or 5 to 12 days after receiving the measles-mumps-rubella vaccine. Study data was reported from 1997 to 2006.

In the JournalsPerspective

Parental, adolescent knowledge of HPV unrelated to vaccination status

September 16, 2014
Recent data show parental and adolescent knowledge of HPV and HPV vaccination was not associated with adolescent vaccination among a predominantly low-income, black…
In the Journals

CDC: Varicella surveillance requires improvement in US

September 15, 2014
Although varicella surveillance has significantly increased, some areas require improvement, such as data transmission from local jurisdictions to CDC and collection of…
In the Journals

Order of vaccine administration could influence patient compliance with HPV4 vaccine

September 5, 2014
Although adolescent girls reported more arm pain after receiving quadrivalent HPV vaccines, physicians should consider administering it prior to other immunizations in…

Prevention of Meningococcal Infections in the First 2 Years of Life

Pediatric Annals, August 2013, Volume 42 Issue 8
CME Educational Objectives1.Review the current epidemiology of meningococcal disease in…
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Immunization An Update

Keck School of Medicine of USC and Pediatric Annals

In the current environment of increasing vaccine refusal, the pediatrician has a powerful role to play as a trusted…
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In the Journals

At-risk girls least likely to be offered HPV vaccine

March 21, 2014
Adolescent girls in the United Kingdom who are at the greatest risk for acquiring HPV are the least likely to be offered the vaccine and to complete…
In the Journals

New rotavirus vaccine showed promising results in India

March 19, 2014
The monovalent human-bovine rotavirus vaccine was effective and well tolerated among infants in India, according to recent study findings published…
In the Journals Perspective

Duration of pertussis PCR positivity a median of 58 days

March 17, 2014
There is a median duration of 58 days for Bordetella pertussis PCR positivity, according to recent study findings published in the Journal of the
In the Journals

MMR, influenza vaccination rates in New York City mirror other communities

March 17, 2014
Measles-mumps-rubella and influenza vaccination among children presenting to a pediatric ED in New York City were comparable to community rates;…
In the Journals

Routine childhood vaccination programs result in substantial cost savings

March 13, 2014
Fully vaccinating children as recommended in the Advisory Committee on Immunization Practices routine immunization schedule results in substantial…
FDA advisory panel decisions

FDA advisory committee unanimously recommends DNA-based HPV test

March 13, 2014
An FDA panel unanimously endorsed the cobas HPV Test as a primary cervical cancer screening tool for women aged 25 years and older.The FDA Medical…
In the Journals

Varicella-associated death likely resulted from immunosuppression

March 4, 2014
The fifth US death of a child who received one dose of varicella vaccine occurred on May 7, 2012, according to recent data published in…

Childhood immunizations in 2014

Infectious Diseases in Children, March 2014
Michael J. Smith, MD, MS
The 2014 routine immunization schedule for children and adolescents has been released. The biggest change to the schedule relates to meningococcal…
Pharmacology Consult

Most vaccine errors related to name confusion

Infectious Diseases in Children, March 2014
Edward A. Bell, PharmD, BCPS
Medical errors have received considerable attention in the medical literature. Many professional societies and organizations have published reports…
Cover Story

Plans underway to prevent future vaccine shortages

Infectious Diseases in Children, March 2014
The state of vaccines, including an increase in coverage rates, introduction of new vaccines and maintenance of vaccine supplies for routinely…
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