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Genetic, structural defects triggered epileptic seizures after vaccination

September 17, 2014

Read the Perspective from Paul A. Offit, MD

Recent data show that genetic or structural defects were the common underlying cause of epilepsy onset after routine vaccination.

Nienke E. Verbeek, MD, MSc, of the University Medical Centre Utrecht in the Netherlands, and colleagues reviewed data from the National Institute for Public Health and Environment in the Netherlands for 990 children who experienced seizures after vaccination during the first 2 years of life. Of these, 26 children were subsequently diagnosed with epilepsy and had seizure onset within 24 hours after inactivated vaccine administration or 5 to 12 days after receiving the measles-mumps-rubella vaccine. Study data was reported from 1997 to 2006.

In the JournalsPerspective

Parental, adolescent knowledge of HPV unrelated to vaccination status

September 16, 2014
Recent data show parental and adolescent knowledge of HPV and HPV vaccination was not associated with adolescent vaccination among a predominantly low-income, black…
In the Journals

CDC: Varicella surveillance requires improvement in US

September 15, 2014
Although varicella surveillance has significantly increased, some areas require improvement, such as data transmission from local jurisdictions to CDC and collection of…
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Order of vaccine administration could influence patient compliance with HPV4 vaccine

September 5, 2014
Although adolescent girls reported more arm pain after receiving quadrivalent HPV vaccines, physicians should consider administering it prior to other immunizations in…
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Pediatric Annals, December 2012, Volume 41 Issue 12
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Immunization An Update

Keck School of Medicine of USC and Pediatric Annals

In the current environment of increasing vaccine refusal, the pediatrician has a powerful role to play as a trusted…
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Pertussis vaccination rates unchanged after epidemic

August 22, 2014
Recent data show no increase in pertussis vaccination rates occurred following the 2011-2012 pertussis outbreak in Washington State.Elizabeth R
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Changing focus of HPV vaccine discussion could increase immunization rates

August 21, 2014
Missed opportunities for HPV vaccination are related to parents’ and physicians’ assumptions about the timing of vaccination relative to…
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Emphasis on child’s direct benefit increased parents’ intent to vaccinate with MMR

August 18, 2014
Parents’ intentions to vaccinate their infants with the measles-mumps-rubella vaccine increased if their physician emphasized benefits directly…
In the Journals

MenC vaccine demonstrates significant, long-lasting herd immunity

August 15, 2014
The meningococcal serogroup C conjugate vaccine provided herd immunity for unvaccinated individuals that lasted at least 10 years, according to…
In the Journals

PCV13 linked to decreased IPD incidence in Denmark

August 4, 2014
Use of the 13-valent pneumococcal conjugate vaccine reduced the incidence of invasive pneumococcal disease and related deaths in Denmark, according…
In the Journals

Pertussis outbreak in Florida highlights outbreak risk in vaccine-averse communities

July 31, 2014
An outbreak of pertussis in a school and religious community in Florida demonstrates the challenges of protecting vaccine-averse communities against…
In the Journals

Children with HIV have increased risk for IPD, varicella zoster hospitalization

July 30, 2014
Children with HIV have an increased risk for hospitalization with invasive pneumococcal disease or varicella zoster compared with children who do not…
In the Journals

WHO: Rotavirus surveillance network requires additional resources

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Nearly half of WHO’s Global Rotavirus Surveillance Network sites met 2008 criteria for documenting disease presence and describing disease…
In the Journals

Web-based decision aid for parents improved MMR vaccine uptake

July 30, 2014
A website offering information to parents about the measles, mumps and rubella vaccine was the most cost-effective means of increasing vaccine…

Blog: Protect your patients traveling to polio-infected countries

July 29, 2014
In his blog, Walter A. Orenstein, MD, professor and associate director of the Emory Vaccine Center at Emory University School of Medicine, reviews…
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