Hypogammaglobulinemia more likely among children with atopic dermatitis

  • July 21, 2014

Pediatric patients with atopic dermatitis were more likely to experience hypogammaglobulinemia compared with healthy children, according to recent study results.

Researchers in Turkey studied 160 children with atopic dermatitis (median age, 14.5 months; 98 boys) and 95 healthy controls (median age, 16 months; 57 boys). The SCORing Atopic Dermatitis Index was used to measure disease severity in the children with atopic dermatitis. Nephelometry was conducted on admission to measure serum immunoglobulin in all children. Hypogammaglobulinemia was defined as “low levels of at least 1 immunoglobulin isotype less than 2 SD of the mean value for age,” the researchers wrote.

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