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FDA approves first Neisseria meningitidis vaccine

October 29, 2014

The FDA announced accelerated approval of Trumenba, a vaccine manufactured by Wyeth Pharmaceuticals, for prevention of Neisseria meningitidis serogroup B among individuals aged 10 to 25 years.

Three randomized studies conducted in the United States and Europe determined efficacy of Trumenba. The studies included approximately 2,800 adolescents. Following receipt of three doses of Trumenba, 82% of patients had antibodies in their blood that combatted four different strains of N. meningitidis serogroup B. Prior to vaccination, only 1% had these antibodies.

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Placebo, agave nectar improved acute cough outcomes among children

October 29, 2014
Recent data show children with acute nocturnal cough benefited more when prescribed agave nectar or placebo vs. no treatment at all, though a placebo effect was…
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AAP updates guidelines for diagnosis, management of bronchiolitis

October 29, 2014
The AAP recently revised the clinical practice guidelines for the diagnosis and management of bronchiolitis among children aged younger than 2 years, last updated in…
In the Journals

Maternal pertussis vaccine during pregnancy protected infants

October 29, 2014
Data from a case-control study confirmed that a pertussis vaccine given during pregnancy protected infants from infection after birth. “Our results provide good…
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Healthy Baby

Managing Cervical Lymphadenitis—A Total Pain in the Neck!

Pediatric Annals, October 2014, Volume 43 Issue 10
Patients presenting with cervical lymphadenitis are a complex and common occurrence in a general pediatric practice…
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CME
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Gender Nonconforming Youth

Pediatric Annals June 2014

Gender identity and pubertal transition to adult gender roles present a complex interplay of genetic, hormonal, and…
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Meeting News Coverage Video
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Marshall discusses the safety, efficacy of a potential combination vaccine for infants

October 28, 2014
PHILADELPHIA — At IDWeek 2014, Gary S. Marshall, MD, chief of pediatric infectious diseases at the University of…
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