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FDA approves first Neisseria meningitidis vaccine

October 29, 2014

The FDA announced accelerated approval of Trumenba, a vaccine manufactured by Wyeth Pharmaceuticals, for prevention of Neisseria meningitidis serogroup B among individuals aged 10 to 25 years.

Three randomized studies conducted in the United States and Europe determined efficacy of Trumenba. The studies included approximately 2,800 adolescents. Following receipt of three doses of Trumenba, 82% of patients had antibodies in their blood that combatted four different strains of N. meningitidis serogroup B. Prior to vaccination, only 1% had these antibodies.

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Placebo, agave nectar improved acute cough outcomes among children

October 29, 2014
Recent data show children with acute nocturnal cough benefited more when prescribed agave nectar or placebo vs. no treatment at all, though a placebo effect was…
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AAP updates guidelines for diagnosis, management of bronchiolitis

October 29, 2014
The AAP recently revised the clinical practice guidelines for the diagnosis and management of bronchiolitis among children aged younger than 2 years, last updated in…
In the Journals

Maternal pertussis vaccine during pregnancy protected infants

October 29, 2014
Data from a case-control study confirmed that a pertussis vaccine given during pregnancy protected infants from infection after birth. “Our results provide good…
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Short Subjects

Benign Recurrent Sixth Nerve Palsy in an Infant

Journal of Pediatric Ophthalmology and Strabismus, Volume -2147483648
Online Only, October 1, 2014
Acquired sixth nerve palsies in children are rare and may indicate serious underlying pathologies such as tumors…
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CME
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Childhood Obesity

Keck School of Medicine of USC and Pediatric Annals

Pediatricians in practice during the past 20 years saw it coming and felt powerless to stop it. At first it was a…
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Meeting News Coverage Video
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Marshall discusses the safety, efficacy of a potential combination vaccine for infants

October 28, 2014
PHILADELPHIA — At IDWeek 2014, Gary S. Marshall, MD, chief of pediatric infectious diseases at the University of…
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