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IGRA TB tests expected to significantly reduce false-positive results compared with TST

November 23, 2014

NEW YORK — Jeffrey R. Starke, MD, an Infectious Diseases in Children Editorial Board member, addresses the growing availability of interferon-gamma release assays over traditionally used tuberculin skin test in children who are at high risk for tuberculosis.

As there is no established ‘gold standard’ for diagnosis of latent tuberculosis infection, both the tuberculin skin test and IGRAs can be used for diagnosis. However, Starke noted that the two commercially available IGRAs – QuantiFERON-TB Gold In Tube and T-SPOT.TB – were more specific than the TST for children who were immunized with Bacillus Calmette-Guérin vaccine and at intermediate risk for TB infection.  

Clarence B. Creech Meeting News Coverage

Clindamycin may be superior therapy for skin, soft tissue infections

November 23, 2014
NEW YORK — Clindamycin may be a more effective treatment for skin and soft tissue infections in children compared with trimethoprim-sulfamethoxazole, according to…
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Review emphasizes careful surveillance in the diagnosis of dermatologic infections

November 22, 2014
NEW YORK — Lawrence F. Eichenfield, MD, chief of pediatric and adolescent dermatology at Rady Children's Hospital-San Diego, outlined a series of case studies…
Cody Meissner Meeting News Coverage

Palivizumab prophylaxis for RSV requires more definitive data

November 22, 2014
NEW YORK — In light of the AAP’s recent recommendations on palivizumab for treatment of respiratory syncytial virus, benefits and disadvantages of the…
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Guest Editorial

Child Neglect

Pediatric Annals, November 2014, Volume 43 Issue 11
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Allergy and Immunology

Keck School of Medicine of USC and Pediatric Annals

When is a cough more than just a cough? This is the challenge that faces every pediatric provider when confronted with…
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Early doxycycline treatment needed to address tick-borne rickettsial disease

November 22, 2014
NEW YORK — Gordon E. Schutze, MD, professor of pediatrics and retrovirology at the Baylor College of
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