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Risk for adverse neonatal outcomes linked to glyburide

March 30, 2015

Gestational diabetes has been increasingly treated with glyburide; however, the medication is associated with a higher risk for newborns to be admitted to the neonatal ICU, have respiratory distress, hypoglycemia, birth injury and be large for gestation age compared with newborns from mothers treated with insulin, according to recent findings.

“The convenience factor makes glyburide an attractive option for women with gestational diabetes, but, in light of these findings, we need to better understand which patients can be managed effectively with this drug,” Michele Jonsson Funk, PhD, of the University of North Carolina at Chapel Hill, told Endocrine Today.

Ian M. Paul, MD, MSc In the Journals

AAP urges standardizing metric unit dosing for all liquid medications

March 30, 2015
In a recently released policy statement, the AAP called for the exclusive use of metric-based dosing for all liquid medications to help prevent unintended…

Experts discuss whether shift in Medicare will reduce costs, improve quality of care

March 30, 2015
In response to concerns over Medicare’s current fee-for-service payment system, the Obama administration announced in January that by 2018 Medicare instead will…
Lawrence Eichenfield FDA News

FDA advisory committee: Severe need for pediatric studies in AD

March 30, 2015
An FDA advisory committee agreed there is an unmet medical need for systemic products, drugs, and biologics, along with additional clinical studies, for the treatment of…
In the Journals

Younger children have highest mortality rate for Ebola

March 27, 2015
Children aged younger than 5 years are more likely to die from Ebola and experience faster progressing illness vs. adults, according to study findings discussed in a…
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Short Subjects

Unusual Presentation of Subretinal Cysticercosis With Hypopyon Uveitis

Journal of Pediatric Ophthalmology and Strabismus, Volume -2147483648
Online Only, March 17, 2015
Subretinal cysticercosis presenting with anterior uveitis and hypopyon is rare. A 7-year-old boy presented with pain…
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Pediatric Metabolic Liver Disorders: Diagnostic Challenges via Case Choice

Pediatric Metabolic Liver Disorders: Diagnostic Challenges via Case Choice

This activity is supported by an educational grant from Synageva Biopharma.

Genetic abnormalities affecting the synthesis or catabolism of metabolic enzymes can lead to the development of serious…
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VIDEO: Recent research promises breakthroughs in pediatric care

March 10, 2015
SAN DIEGO — In this video exclusive, Mark A. Sperling, MD, emeritus profess of pediatrics and endocrinology and…
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