Neuraminadase inhibitors not always beneficial to patients with influenza

  • April 16, 2014

A recent Cochrane review recommends that the guidance on using neuraminidase inhibitors be reviewed to take into account the small benefit compared with the risk of harm, according to data published in the British Medical Journal and The Cochrane Library.

“We now have the most robust, comprehensive review on ‘neuraminidase inhibitors’ that exists,” David Tovey, MD, editor-in-chief of the Cochrane Library, said in a press release. “Initially thought to reduce hospitalizations and serious complications from influenza, the review highlights that Tamiflu is not proven to do this, and it also seems to lead to harmful effects that were not fully reported in the original publications. This shows the importance of ensuring that trial data are transparent and accessible.”

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