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Rapidly waning Tdap offers little long-term protection against pertussis

Rapidly waning Tdap offers little long-term protection against pertussis
February 5, 2016

Tdap vaccine waned rapidly and provided only limited, short-term protection against pertussis when administered to adolescents as a booster for DTaP, according to recent research in Pediatrics.

“This study investigated the effectiveness of Tdap against pertussis in a highly vaccinated population during two successive epidemics,” Nicola P. Klein, MD, PhD, of the Northern California Kaiser Permanente Vaccine Study Center, and colleagues wrote. “We demonstrate that among a cohort of teenagers who have exclusively received acellular pertussis vaccines, Tdap provides moderate protection 1 year after vaccination and then protection wanes rapidly.”

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