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IMAGO: LUM001 fails to reduce bile acids, pruritus in pediatric patients with ALGS

April 26, 2015

VIENNA — Serum bile acids and pruritus remained unchanged in pediatric patients with allagile syndrome after treatment with LUM001, according to a late breaker presentation at the 2015 International Liver Congress.

“Alagille syndrome is a genetic disorder that often involves cholestasis,” Alastair Baker, MB ChB, FRCP, FRCPCH, pediatric liver consultant, King’s College Hospital, London, said in his presentation. “Accumulation of bile acids may lead to progressive liver disease and severe pruritus may be an indication for liver transplant.”

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