April 20, 2015
During the first 24 hours following simultaneous bilateral total knee arthroplasty, periarticular injection was associated with better pain relief and decreased opioid-related side effects compared with epidural analgesia, according to study results.
Researchers randomly assigned 71 patients undergoing total knee arthroplasty (TKA) to receive periarticular injection or epidural analgesia. All patients received identical perioperative interventions, including spinal anesthesia, surgical techniques and postoperative medication protocols. During the initial 24-hour postoperative period, the researchers measured postoperative pain at rest with the use of a 100-mm VAS. The researchers also used the area under the curve to calculate the cumulative VAS, which was compared between the two groups.