January 29, 2015
In a recently published study, researchers determined that to effectively treat giant cell tumors of bone with zoledronic acid, a hybrid including artificial bone would be needed.
The researchers evaluated five patients with giant cell tumor of bone treated with zoledronic acid between 2008 and 2013 at a single institution. The tumors were either grade II or III on the Campanacci scale. Four patients received zoledronic acid with artificial bone, and one patient was administered the treatment without it. Surgically resected specimens were utilized to determine the patients’ histologic response.