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ARCH study: Romosozumab data show increased cardiovascular risk

May 22, 2017

Treatment with the anti-sclerostin monoclonal antibody romosozumab resulted in fewer new fractures in postmenopausal women with high-risk osteoporosis compared with alendronate, according to a press release from Amgen.

However, romosozumab (Evenity, Amgen and UCB) resulted in more cardiovascular serious adverse events (2.5%) compared with alendronate (1.9%) at 12 months, according to the release.

In the Journals

Dual mini-fragment plating technique yielded low rates of secondary surgery

May 18, 2017
Patients with clavicular shaft fractures treated with a dual mini-fragment plating technique experienced low rates of secondary surgery due to symptomatic implant…
Meeting News

Speaker discusses opioid crisis through a population health perspective

May 17, 2017
PHILADELPHIA — The key issue in opioid abuse is that addiction thrives among populations marked by violence, homelessness and employment, according to a speaker at…
Orthopedics Today Grand Rounds

A 77-year-old woman with right hip fluid collection, altered mental status

Orthopedics Today, May 2017
Eric M. Cohen, MD; Shaun P. Patel, MD; Valentin Antoci Jr., MD, PhD
A 77-year-old woman, who was found down at her home, was brought to the hospital by ambulance. Her mental status was altered. The patient’s medical history was…
Feature Article

Biomechanical and Cost Comparisons of Near-Far and Pin-Bar Constructs

Orthopedics, March/April 2017, Volume 40 Issue 2
Orthopedic dogma states that external fixator stiffness is improved by placing 1 pin close to the fracture and 1 as…
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CME

Effect of Topical Tranexamic Acid in Reducing Bleeding and Transfusions in TKA: May 2015

Intravenous tranexamic acid (TXA) has been identified to be effective in total knee arthroplasty (TKA), but the effect…
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Arthroscopy Association of North America Annual Meeting

Arthroscopy Association of North America Annual Meeting

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Meeting News

VIDEO: Speakers discuss limb lengthening, hip instability

March 1, 2017
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ARCH study: Romosozumab data show increased cardiovascular risk

May 22, 2017
Treatment with the anti-sclerostin monoclonal antibody romosozumab resulted in fewer new fractures in postmenopausal women with high-risk…

In the Journals

Dual mini-fragment plating technique yielded low rates of secondary surgery

May 18, 2017
Patients with clavicular shaft fractures treated with a dual mini-fragment plating technique experienced low rates of secondary surgery due to…

Meeting News

Speaker discusses opioid crisis through a population health perspective

May 17, 2017
PHILADELPHIA — The key issue in opioid abuse is that addiction thrives among populations marked by violence, homelessness and employment…

Orthopedics Today Grand Rounds

A 77-year-old woman with right hip fluid collection, altered mental status

Orthopedics Today, May 2017
Eric M. Cohen, MD; Shaun P. Patel, MD; Valentin Antoci Jr., MD, PhD
A 77-year-old woman, who was found down at her home, was brought to the hospital by ambulance. Her mental status was altered. The patient’s…

Tips & Techniques

Percutaneous Screw Fixation for Scaphoid Fractures

Orthopedics
Online Advanced Release, May 15, 2017
Treatment of nondisplaced scaphoid waist fractures has evolved from conventional cast immobilization to percutaneous screw insertion. This study…

Feature Article

Effect of Lymphedema Treatment for Management of Acute Pilon Fractures

Orthopedics
Online Advanced Release, May 15, 2017
Pilon fractures are high-energy injuries that often result in considerable edema and compromise of the soft tissue envelope of the ankle. These…

In the Journals

ACP issues guidelines to reduce fracture risk in women with osteoporosis

May 8, 2017
Today, the ACP released an updated evidence-based clinical practice guideline strongly recommending that physicians treat women with osteoporosis…

Feature Article

Early Versus Late Weight-Bearing Protocols for Surgically Managed Posterior Wall Acetabular Fractures

Orthopedics
Online Advanced Release, May 8, 2017
Despite overall improved outcomes with open reduction and internal fixation of acetabular fractures, posterior wall fractures show disproportionately…

In the Journals

Sleeping pills double the risk for hip fracture

May 4, 2017
Patients who were middle-aged and taking benzodiazepines or nonbenzodiazepine hypnotics for 2 weeks or less were at increased risk for hip fracture…

In the Journals

Significantly greater transfusion rate found with reamer irrigator system for bone graft harvest

May 4, 2017
Use of a reamer irrigator aspirator system for bone graft harvest was linked to a significantly greater transfusion rate compared with the use of…

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