Osteoporosis

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ARCH study: Romosozumab data show increased cardiovascular risk

May 22, 2017

Treatment with the anti-sclerostin monoclonal antibody romosozumab resulted in fewer new fractures in postmenopausal women with high-risk osteoporosis compared with alendronate, according to a press release from Amgen.

However, romosozumab (Evenity, Amgen and UCB) resulted in more cardiovascular serious adverse events (2.5%) compared with alendronate (1.9%) at 12 months, according to the release.

In the Journals

ACP issues guidelines to reduce fracture risk in women with osteoporosis

May 8, 2017
Today, the ACP released an updated evidence-based clinical practice guideline strongly recommending that physicians treat women with osteoporosis with denosumab or…
In the Journals

Hormone therapy linked with decreased fracture risk for postmenopausal women

May 5, 2017
Among postmenopausal women, investigators found the risk of fracture decreased with the use of hormone therapy. Moreover, the findings were particularly true for women…
FDA News

FDA approves Tymlos for postmenopausal women with osteoporosis

April 28, 2017
The FDA today approved an abaloparatide injection for the treatment of postmenopausal women with osteoporosis at high risk for fracture, according to a press release…
Feature Article

Evaluation of a Novel Osteoporotic Drug Delivery System In Vitro: Alendronate-loaded Calcium Phosphate Cement

Orthopedics, August/September 2010, Volume 33 Issue 8
As a new drug delivery system, calcium phosphate cement was fabricated with different concentrations of alendronate (2…
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CME

Bundled Payments in Orthopedic Surgery: February 2015

Bundled payments, the idea of paying a single price for a bundle of goods and services, is a financial concept familiar…
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Arthroscopy Association of North America Annual Meeting

Arthroscopy Association of North America Annual Meeting

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Meeting News Coverage

VIDEO: Long-term oral bisphosphonate use mildly increases risk for osteonecrosis of the jaw

September 20, 2016
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ARCH study: Romosozumab data show increased cardiovascular risk

May 22, 2017
Treatment with the anti-sclerostin monoclonal antibody romosozumab resulted in fewer new fractures in postmenopausal women with high-risk…

In the Journals

ACP issues guidelines to reduce fracture risk in women with osteoporosis

May 8, 2017
Today, the ACP released an updated evidence-based clinical practice guideline strongly recommending that physicians treat women with osteoporosis…

In the Journals

Hormone therapy linked with decreased fracture risk for postmenopausal women

May 5, 2017
Among postmenopausal women, investigators found the risk of fracture decreased with the use of hormone therapy. Moreover, the findings were…

FDA News

FDA approves Tymlos for postmenopausal women with osteoporosis

April 28, 2017
The FDA today approved an abaloparatide injection for the treatment of postmenopausal women with osteoporosis at high risk for fracture, according to…

In the Journals

Benefits, harms of osteoporosis medications in chronic kidney disease uncertain

April 11, 2017
There are no clearly established effects of osteoporosis medications on bone mineral density, fracture risk and safety in patients with chronic…

CDC reports FRAX-based 10-year probability of hip, major osteoporotic fractures in middle-aged adults

April 6, 2017
The National Center for Health Statistics of the CDC recently published data that offered a FRAX-based estimation of the 10-year probability of…

In the Journals

Denosumab found safe in long-term extension trial

March 23, 2017
Denosumab in the treatment of patients with osteoporosis did not show any increase in common adverse events in a long-term trial, according to…

In the Journals

Researchers identify possible early warning signs for osteoporosis in South Asian women

March 22, 2017
In premenopausal South Asian women, researchers identified higher levels of urinary N-telopeptide — a by-product for bone resorption —…

Meeting News

Men had greater risk for death after osteoporosis-related fracture compared with women

March 21, 2017
SAN DIEGO — Compared with women, men had a greater risk for death after an osteoporosis-related fracture, according to a press release and…

In the Journals

Women with hip fractures need better follow-up monitoring, management for osteoporosis

March 2, 2017
Screening and treatment for osteoporosis in postmenopausal women after a hip fracture is alarmingly low, with fewer than one in five women aged 50…

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