Researchers recommend knee fusion to treat infection after first failed TKA two-stage exchange

  • August 27, 2013

PHILADELPHIA – Researchers from the University of Pennsylvania created a decision tree of treatment options following a failed two-stage exchange in total knee arthroplasty and found knee arthrodesis was most effective in the treatment of infection and preservation of knee function.

“Fusion became the dominant treatment strategy in almost every iteration of the decision tree,” Chancellor F. Gray, MD, stated in his presentation at the Musculoskeletal Infection Society Annual Meeting, here. “As a reference, even if the utility of a revision is set in equivalence to a primary knee – in other words, if you said all your two-stage revisions did as well as all your primary knee patients – and you set the probability of success to a commonly quoted 90%, which is substantially higher than we found in our study, fusion is still clearly the dominant choice in the tree.”

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Additional headlines from Musculoskeletal Infection Society Annual Meeting