Researchers find lower than reported incidence of joint infection in HIV population after TJA

Researchers found a lower than reported incidence of joint infection after total joint arthroplasty in patients with HIV.

“While there may be a slight increase, current findings do not support prior findings of a large increase in infection rate in the HIV population,” Brian M. Capogna, MD, and colleagues wrote in the study.

Capogna and colleagues compared 69 patients with HIV to 138 matched control patients, all of whom were undergoing total joint arthroplasty (TJA), according to the abstract. The reasons for surgery differed between the HIV group and the control group: patients with HIV most commonly required total knee arthroplasty (TKA) due to osteoarthritis and total hip arthroplasty (THA) for avascular necrosis. Patients in the control group most commonly required TKA or THA for osteoarthritis.

orthomind

They found that HIV-infected TJA patients were 6.22 times more likely to develop a joint infection after surgery compared to the control group (4.4% vs. 0.79%). There were decreases in the Kaplan-Meier survival curves for infection-free and revision-free survival in the HIV group, but the results were not statistically significant, according to the abstract.

Disclosure: One of the authors (Kim) is on the speaker’s bureau for and receives research support from Ferring Pharmaceuticals.