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Greater number of mesenchymal stem cells released with fibrous synovium in culture model

May 15, 2017

Investigators of this study found fibrous synovium compared with adipose synovium release a greater number of mesenchymal stem cells in a suspended synovium culture model.

Researchers harvested human synovial tissue from knee joints during the total knee arthroplasty of 34 patients with osteoarthritis. Investigators suspended 1 gram of synovium with a thread in a bottle filled with 40 mL of culture medium. A 3.5-cm diameter culture dish was at the bottom of the bottle and investigators examined the culture dish after 7 days. Multipotentiality and surface epitopes were analyzed for the cells harvested. Investigators compared the number of colonies derived from the fibrous synovium and the adipose synovium.

Meeting News

Etanercept seen as effective against bone marrow lesions in patients with hand OA

May 8, 2017
LAS VEGAS — Etanercept was effective for the inhibition of bone marrow lesions in patients with erosive hand osteoarthritis, according to a presenter here at the…
Meeting News

Etanercept linked with pain relief in prespecified per-protocol analysis of symptomatic hand OA

April 28, 2017
LAS VEGAS — Although investigators found non-superiority of etanercept compared with placebo overall in their study, they noted an analysis of patients with…
Meeting News

Adalimumab did not provide significant relief of pain, synovitis in patients with hand OA

April 28, 2017
LAS VEGAS — Patients with erosive hand osteoarthritis treated with adalimumab experienced no significant alleviation of pain, synovitis or bone marrow lesions…
Feature Article

Human Dermal Allograft for Massive Rotator Cuff Tears

Orthopedics, December/January 2014, Volume 37 Issue 12
Previously published studies reported variable results using various suture techniques and reconstruction options for…
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CME

Venous Thromboembolism Prophylaxis After Total Joint Arthroplasty: April 2015

Venous Thromboembolism Prophylaxis After Total Joint Arthroplasty
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Arthroscopy Association of North America Annual Meeting

Arthroscopy Association of North America Annual Meeting

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Meeting News Coverage

VIDEO: A look at developmental biology and articular cartilage repair

June 17, 2015
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In the Journals

Greater number of mesenchymal stem cells released with fibrous synovium in culture model

May 15, 2017
Investigators of this study found fibrous synovium compared with adipose synovium release a greater number of mesenchymal stem cells in a suspended…

Meeting News

Etanercept seen as effective against bone marrow lesions in patients with hand OA

May 8, 2017
LAS VEGAS — Etanercept was effective for the inhibition of bone marrow lesions in patients with erosive hand osteoarthritis, according to a…

Meeting News

Etanercept linked with pain relief in prespecified per-protocol analysis of symptomatic hand OA

April 28, 2017
LAS VEGAS — Although investigators found non-superiority of etanercept compared with placebo overall in their study, they noted an analysis of…

Meeting News

Adalimumab did not provide significant relief of pain, synovitis in patients with hand OA

April 28, 2017
LAS VEGAS — Patients with erosive hand osteoarthritis treated with adalimumab experienced no significant alleviation of pain, synovitis or bone…

DePuy Synthes acquires 3-D printing technologies from Tissue Regeneration Systems

April 20, 2017
DePuy Synthes Products Inc. has acquired 3-D printing technology from Tissue Regeneration Systems Inc. According to a company press release, the deal…

In the Journals

Athletes with shoulder instability had significantly lower levels of specific collagen biomarker

April 19, 2017
Athletes with shoulder instability had significantly lower levels of the cartilage degradation marker collagen type II cleavage compared to athletes…

From OT Europe

EFORT Open Reviews: A round-up of recently published articles

Orthopaedics Today Europe, April 2017
EFORT Open Reviews is the new open access journal from EFORT and The British Editorial Society of Bone & Joint Surgery. All articles are free to…

HA-BMAC yielded more durable knee cartilage repair at 5 years vs microfracture

Orthopedics Today, March 2017
A hyaluronic acid-based scaffold with bone marrow aspirate concentrate used in patients with a chondral injury achieved better outcomes and more…

From OT Europe

Bone regeneration trial under way to identify nonunion solutions

Orthopaedics Today Europe, February 2017
Enrique Gómez-Barrena, MD, PhD
Editor’s Note: This article by Enrique Gómez Barrena, MD, Vice Chairman Education Committee – Basic Research Group of EFORT, is the

In the Journals

Testosterone treatment improves bone density, strength in older men

February 22, 2017
One year of testosterone treatment significantly increased volumetric bone mineral density and estimated bone strength in men aged 65 years and…

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