April 28, 2017
Male sex, high myopia, higher central corneal thickness, lower K value, corneal haze, type of steroid used and length of therapy were associated with a higher risk of steroid-induced ocular hypertension after PRK surgery, a study showed.
The data from 3,566 eyes of 1,783 patients who had PRK with five different surgeons were retrospectively analyzed. Different steroid regimens were prescribed after surgery, with either dexamethasone or fluorometholone or both consecutively. The schedule was one drop every 6 hours for all, but length of treatment varied between 2 and 8 weeks. Ocular hypertension, defined as IOP elevation of 25% during steroid treatment and return to baseline after discontinuation, occurred in 106 eyes (2.97%).