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Amino acid peptide improves signs, symptoms in severe dry eye

May 22, 2015

Patients with chronic graft-vs.-host disease who were treated with thymosin β4 eye drops (RGN-259, 0.1%) experienced statistically significant improvements in signs and symptoms, according to a study published in Cornea.

Sosne and colleagues conducted a randomized, double-masked, placebo-controlled phase 2 clinical trial at two U.S. sites. Researchers treated nine men and women older than 18 years with severe dry eye with either Tβ4, a naturally occurring 43 amino acid peptide found in high concentrations in most tissues and cells, or placebo six times a day. The 56-day trial included a 28-day follow-up.

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In the Journals

Amino acid peptide improves signs, symptoms in severe dry eye

May 22, 2015
Patients with chronic graft-vs.-host disease who were treated with thymosin β4 eye drops (RGN-259, 0.1%) experienced statistically significant…
Perspectives on Glaucoma

Phaco effective in reducing IOP for PACG patients

May 21, 2015
Phacoemulsification resulted in small and moderate intraocular pressure reductions in primary open-angle glaucoma and pseudoexfoliation glaucoma…
Perspectives on Glaucoma

Specific patients more likely to require interventions after LPI

May 20, 2015
Older patients, as well as other specific patient groups, were found to require more medications after laser peripheral iridotomy, researchers…
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Patients experience multiple barriers in glaucoma medication adherence

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Eye care professionals have to address each patient's adherence individually, researchers reported in a study recently published in…

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Azithromycin recommended for MGD

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Number of eye drop bottles associated with incorrect usage

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PCON Coverstory April 2015 PCON Reports

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FDA News

FDA grants priority review designation for lifitegrast

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The FDA has accepted Shire’s new drug application and granted priority review designation for lifitegrast to treat dry eye disease in adults…
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