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PRK with cross-linking markedly reduces keratocyte, nerve density

August 22, 2014

PRK combined with corneal collagen cross-linking had a transient effect on corneal innervation and a significant effect on keratocyte density for up to 4 years postoperatively, researchers found.

The researchers prospectively analyzed 17 eyes of 17 patients with progressive keratoconus who underwent PRK with corneal collagen cross-linking. Confocal microscopy was used preoperatively and 1, 3, 6, 12, 18 and 48 months postoperatively to assess corneal morphology. Primary study outcome measures were mean superficial epithelial cell density, mean basal epithelial cell density and mean anterior and mid/posterior keratocyte density. Stromal backscatter, sub-basal and stromal nerve density, and mean endothelial cell density were also evaluated.

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Bacterial Conjunctivitis Challenge

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How much do you know about bacterial conjunctivitis treatment? Each question on this challenge features expert…
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In the Journals

PRK with cross-linking markedly reduces keratocyte, nerve density

August 22, 2014
PRK combined with corneal collagen cross-linking had a transient effect on corneal innervation and a significant effect on keratocyte density for up…

NovaBay discontinues studies on NVC-422 for viral conjunctivitis

August 21, 2014
NovaBay Pharmaceuticals announced in a press release that its phase 2 clinical study for NVC-422 ophthalmic formulation for patients with adenoviral…
In the Journals

Incision placement in cataract surgery affects corneal HOAs, not vision quality

August 19, 2014
Researchers found that the location of corneal incisions in cataract surgery affected corneal higher-order aberrations, primarily to the posterior…
In the Journals

Topical tacrolimus reduces signs, symptoms of allergic conjunctivitis

August 19, 2014
Tacrolimus eye drops treated recalcitrant allergic conjunctivitis with proliferative lesions or corneal involvement, according to a study.The…
In the Journals

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