April 21, 2017
Repeated anti-VEGF injections in patients with age-related macular degeneration reduces aqueous outflow facility, particularly in patients with higher-than-normal intraocular pressure at baseline, according to a study.
Patients receiving unilateral anti-VEGF treatment were recruited, so that the fellow eye could be used as control. According to injection frequency, they were divided in a low injection group (10 injections) and a high injection group (20 injections), made up of 20 and 22 patients, respectively. A further division was made between patients with baseline ocular hypertension and normotensive patients. IOP and tonographic outflow facility were measured and compared between eyes and between groups.