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Gene therapy yields ‘modest’ impact on retinal sensitivity in Leber’s congenital amaurosis

May 5, 2015

Gene therapy resulted in a modest and temporary improvement in retinal sensitivity among patients with Leber’s congenital amaurosis, according to a study.

In a phase 1/2 open-label trial, 12 patients with early-onset, severe retinal dystrophy caused by mutations in RPE65 underwent gene therapy with a recombinant adeno-associated virus 2/2 (rAAV2/2) vector, rAAV2/2.hRPE65p.hRPE65, carrying RPE65 complementary DNA.

VIDEO: Study shows cataract surgery safe in patients undergoing anti-VEGF therapy Meeting News CoverageVideo

VIDEO: Study shows cataract surgery safe in patients undergoing anti-VEGF therapy

May 5, 2015
DENVER — At the Association for Research in Vision and Ophthalmology meeting here, Andrew Moshfeghi, MD, discusses his poster presentation on a sub-group analysis from…
VIDEO: Frank G. Holz, MD, receives Heidelberg Engineering’s Xtreme Research Award Meeting News CoverageVideo

VIDEO: Frank G. Holz, MD, receives Heidelberg Engineering’s Xtreme Research Award

May 5, 2015
DENVER — At the Association for Research in Vision and Ophthalmology meeting here, Frank G. Holz, MD, discusses the Xtreme Research Award and the latest research into…
VIDEO: Study shows improvement in diabetic retinopathy with ranibizumab Meeting News CoverageVideo

VIDEO: Study shows improvement in diabetic retinopathy with ranibizumab

May 5, 2015
DENVER — At the Association for Research in Vision and Ophthalmology meeting here, Jennifer K. Sun, MD, discusses the effect of ranibizumab on diabetic retinopathy in…
Meeting News Coverage

Ultra-widefield imaging increases diabetic retinopathy detection

May 5, 2015
DENVER — Ultra-widefield imaging may double diabetic retinopathy detection and referral rates while decreasing the ungradable rate in telemedicine programs…
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Practical Retina

Comparing Aflibercept, Bevacizumab, and Ranibizumab for DME: Analysis of DRCR Protocol T

Ophthalmic Surgery, Lasers and Imaging Retina, March 2015, Volume 46 Issue 3
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CME
OCT Angiography: The Next ‘Big Thing’ in Retinal Imaging

OCT Angiography: The Next ‘Big Thing’ in Retinal Imaging

This activity is supported by an educational grant from Carl Zeiss Meditec, Inc.

Optical coherence tomography (OCT) angiography has the potential to significantly improve clinicians’ ability to view…
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Meeting News Coverage Video
VIDEO: Frank G. Holz, MD, receives Heidelberg Engineering’s Xtreme Research Award

VIDEO: Frank G. Holz, MD, receives Heidelberg Engineering’s Xtreme Research Award

May 5, 2015
DENVER — At the Association for Research in Vision and Ophthalmology meeting here, Frank G. Holz, MD, discusses the…
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