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Alcon drug meets primary endpoint of change in BCVA for wet AMD

March 2, 2015

RTH258 met its primary endpoint of mean change in best corrected visual acuity from baseline to week 12 in a phase 2 study of patients with neovascular age-related macular degeneration, Alcon announced in a press release.

RTH258, formerly known as ESBA 1008, is a novel, single-chain antibody fragment, which at a dose of 6 mg was compared with 2 mg Eylea (aflibercept, Regeneron) in a prospective, multicenter, randomized, double-masked study of 90 eyes.

Meeting News Coverage

Progressive retinal nerve fiber layer loss associated with quality of life measure changes

March 2, 2015
CORONADO, Calif. — Progressive retinal nerve fiber layer thickness loss was associated with loss of quality of life in glaucoma patients, even after adjustment for…
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VIDEO: Small pupil issues in femtosecond laser cataract surgery

March 2, 2015
ISTANBUL – At the ESCRS Winter Meeting, Boris Malyugin, MD, PhD, talks about small pupil issues in femtosecond laser cataract surgery. Laser shots applied to the…
In the Journals

Fluorometholone treatment faster than cyclosporine A for Sjögren’s syndrome ocular dryness

March 2, 2015
Successful treatment of ocular dryness with fluorometholone occurred faster than treatment with cyclosporine A in patients with Sjögren’s syndrome, according…
Meeting News Coverage

Early studies examine neuroregeneration in optic neuropathies

March 2, 2015
CORONADO, Calif. — Whether called neuroprotection, neuroenhancement or regeneration, any of these would be a major step forward in restoring vision in optic…
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Original Article

Corneal Asymmetry Analysis by Pentacam Scheimpflug Tomography for Keratoconus Diagnosis

Journal of Refractive Surgery, February 2015, Volume 31 Issue 2
To evaluate intereye corneal asymmetry in Pentacam (Oculus Optikgeräte GmbH, Wetzlar, Germany) indices as a diagnostic…
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Intravitreal Interventions

Intravitreal Interventions – Volume 3, Number 3

This activity is supported by educational grants from Genentech, Inc. and Regeneron Pharmaceuticals, Inc.

During the past decade, retinal pharmacology has come into its own. Intravitreal use of corticosteroids, anti-vascular…
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Meeting News Coverage Video
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VIDEO: Utility of ICG angiography in 2015

March 1, 2015
WAILEA, Hawaii – At Retina 2015, Jay S. Duker, MD, talks about how ICG angiography should be apart of retinal…
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