August 27, 2014
Results from a meta-analysis showed no associations between cholesterol measures, history of statin use or lipid pathway genes and the incidence and progression of age-related macular degeneration, according to researchers.
The meta-analysis included three population-based cohorts: the Beaver Dam Eye Study, Blue Mountain Eye Study and Rotterdam Study, for a total of 6,950 participants. The researchers followed patients for 20 years, with examinations every 5 years. During follow-ups, hazard ratios associated with lipid levels and lipid pathway genes were calculated through the use of random-effects inverse-weighted meta-analysis models adjusted for known AMD risk factors.