Imaging: Case Report
- Ophthalmic Surgery, Lasers and Imaging
A 59-year-old woman presented with bilateral, peripheral, circular corneal infiltrates. There was a clear zone separating the outer margin of the degeneration from the limbus in both eyes. The inner margins were indistinct. Ultra-high–resolution optical coherence tomography (UHR-OCT) imaging demonstrated subepithelial infiltrations with epithelial thinning and corneal surface elevation. The infiltrate was accompanied by significant stromal scarring, which reached deep layers of the corneal stroma. UHR-OCT findings were consistent with Salzmann nodular degeneration. UHR-OCT can be used as an optical biopsy to diagnose atypical corneal degenerations without tissue sampling.
From the Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida.
Presented at the CEDAS meeting at the Association for Research in Vision and Ophthalmology annual meeting; May 2–6, 2010; Fort Lauderdale, Florida.
Supported by an unrestricted grant from NIH Center Grant P30 EY014801 and Research to Prevent Blindness.
Address correspondence to Sonia H. Yoo, MD, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 N.W. 17 Street, Miami, FL 33136. E-mail: firstname.lastname@example.org