- Ophthalmic Surgery, Lasers and Imaging
- July/August 2012 - Volume 43 · Issue 4: 284-290
BACKGROUND AND OBJECTIVE:
To study the safety and efficacy of “graded” subthreshold transpupillary thermotherapy (TTT), a novel treatment protocol for chronic central serous chorioretinopathy (CSC) and an alternative to photodynamic therapy (PDT).
PATIENTS AND METHODS:
This retrospective pilot study included 10 eyes with chronic CSC that underwent TTT with 810-nm continuous diode laser treatment using a subthreshold power (60% reduced from threshold) for 60 seconds. Treatment was repeated at 20% increase in power from the baseline if submacular fluid persisted on optical coherence tomography (OCT) after 1 month (graded fashion).
The mean chronic CSC duration was 20.3 ± 8.3 months. Eight eyes (80%) showed resolution of CSC on OCT. Mean number of TTT sittings required was 1.5. Although 5 eyes (50%) had 3 or more lines of improvement in Snellen visual acuity, 3 eyes (30%) had up to 2 lines of improvement. None of the patients developed macular burn or scar.
The safety enhanced graded subthreshold TTT was beneficial in patients with chronic CSC.
From the Department of Retina and Ocular Oncology, Aravind Eye Hospital, Coimbatore, Tamil Nadu, India.
Presented at the annual meeting of the American Academy of Ophthalmology, October 24–27, 2009, San Francisco, California.
The authors have no financial or proprietary interest in the materials presented herein.
Address correspondence to George J. Manayath, FRCS, Department of Retina & Ocular Oncology, Aravind Eye Hospital, Avinashi Road, Coimbatore 641 014, Tamil Nadu, India. E-mail: email@example.com
Received: February 21, 2012
Accepted: April 02, 2012