- Journal of Refractive Surgery
- October 2011 - Volume 27 · Issue 10: 759-763
To assess the corneal architecture and reproducibility of LASIK flap thickness created by the Amadeus II mechanical microkeratome (Ziemer Ophthalmic Systems AG) using Fourier-domain optical coherence tomography (OCT; Optovue Inc).
Anterior segment Fourier-domain OCT was used to analyze the morphology of 58 LASIK flaps from 30 patients created with the Amadeus II microkeratome 140-μm head and ML7090CLB blades (Med-Logics Inc) at 2 weeks postoperatively. Flap thickness was assessed at 10 points across the central 6 mm of the cornea (horizontal and vertical meridians). Postoperative central corneal flap thickness measured by Fourier-domain OCT was compared with intraoperative ultrasound pachymetry measurements.
No significant difference was noted between central flap thickness measured by intraoperative pachymetry (107.2±14 μm) and postoperative OCT (111.7±11 μm; P=.07, correlation coefficient=0.86). Fourier-domain OCT measurements demonstrated functionally planar flap architecture (standard deviation [SD] of thickness across the flap=4.9 μm, SD range across the flap=2 to 9 μm) for the microkeratome flaps.
The Amadeus II microkeratome with Med-Logics blades created thin, reproducible, functionally planar flaps as measured by Fourier-domain OCT. Central flap thickness measured by intraoperative ultrasound pachymetry was equivalent to that measured 2 weeks postoperatively by OCT.
From Emory Vision & Emory Eye Center, Atlanta, Georgia.
Supported in part by Research to Prevent Blindness Inc, New York, New York; and the National Institutes of Health Core Grant P30 EYO6360, Bethesda, Maryland.
The authors have no financial interests in the materials presented herein.
Correspondence: J. Bradley Randleman, MD, Emory Vision, 875 Johnson Ferry Rd, Ste 100, Atlanta, GA 30322. E-mail: Jrandle@emory.edu