- Journal of Refractive Surgery
- January 2012 - Volume 28 · Issue 1: 72-74
To analyze in vivo structural properties of a case with interface haze that developed after femtosecond laser–assisted LASIK.
A 42-year-old man underwent uncomplicated LASIK. Four months after the surgery he developed regression of his refractive error and interface haze in both eyes. Flap thickness was calculated as 73 μm and 81 μm in the right and left eyes, respectively. A novel ultra-high-resolution spectral domain optical coherence tomography (OCT) system was used to demonstrate in vivo morphology of the cornea. On ultra-high-resolution OCT, haze was demonstrated as increased bright white reflectivity of the flap interface. Areas of focal disruption of the basement membrane and Bowman layer corresponded with the most significant areas of interface haze.
Our results support the hypothesis that haze after femtosecond LASIK may be a result of damage to the basement membrane and Bowman layer of the cornea.
From Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida.
Dr Yoo is a consultant for Carl Zeiss Meditec. The remaining authors have no financial interest in the materials presented herein.
This research was supported by an unrestricted grant from NIH Center Grant P30 EY014801 and Research to Prevent Blindness.
Presented at the American Society of Cataract and Refractive Surgery meeting; March 25–29, 2011; San Diego, California.
Correspondence: Sonia H. Yoo, MD, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17 St, Miami, FL 33136. Tel: 305.326.6322; Fax: 305.326.6337; E-mail: firstname.lastname@example.org
Received: January 23, 2011
Accepted: October 13, 2011
Posted Online: December 09, 2011