- Journal of Refractive Surgery
- April 2012 - Volume 28 · Issue 4: 267-274
To evaluate visual and aberrometric outcomes and position of the AcrySof Cachet (Alcon Laboratories Inc) angle-supported phakic intraocular lens (PIOL) for correction of myopia in adults.
This prospective study included 36 consecutive eyes with moderate to high myopia in which an AcrySof Cachet PIOL was implanted to minimize refractive error. Follow-up was up to 1 year.
Mean manifest spherical equivalent refraction reduced significantly from −14.90±0.90 diopters (D) to −0.29±0.30 D at 1 month and remained stable at 1 year (P<.001). Mean uncorrected distance visual acuity was ⩾0.1 logMAR (20/20 Snellen) in 56% of patients and ⩾0.3 logMAR (20/25 Snellen) in 100% of patients. Corrected distance visual acuity was ⩾0.1 logMAR (20/20 Snellen) in 78% of patients and ⩾0.3 logMAR (20/25 Snellen) in 100% of patients. Mean endothelium–PIOL distance and mean PIOL–crystalline distance were within recommended values at all postoperative evaluations. Statistically significant variations for these variables were not observed. Anterior chamber depth, safety center distance, and vault center distance showed significant reduction after accommodation (P<.01). Anterior chamber depth and safety center distance significantly increased after pupil dilation (P⩽.01). Mean percentage of endothelial cell loss was 4.04% at 1 year. The root-mean-square of total higher order aberrations and spherical, coma, and trefoil aberrations did not change significantly from pre- to postoperatively.
The AcrySof Cachet PIOL was effective in the correction of moderate to high myopia and provided excellent visual performance with no modification of physiologic ocular wavefront error. Adequate distance from the cornea and crystalline lens was maintained with no significant change during follow-up and under different environmental conditions.
From the Department of Medicine and Science of Aging, Eye Clinic (L. Mastropasqua, Toto, Vecchiarino, Doronzo, R. Mastropasqua) and Fondazione Università “G. d’Annunzio,” Center of Excellence on Aging and Department of Biomedical Science (Di Nicola), University “G. d’Annunzio,” Chieti-Pescara, Italy.
The authors have no proprietary interest in the materials presented herein.
Drs L. Mastropasqua and Toto contributed equally to this work.
Correspondence: Lisa Toto, MD, PhD, Eye Clinic, University “G. d’Annunzio” Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy. Tel: 39 0871 358410; Fax: 39 0871 358794; E-mail: email@example.com
Received: August 22, 2011
Accepted: December 19, 2011
Posted Online: March 01, 2012