- Journal of Pediatric Ophthalmology and Strabismus
A 22-month-old girl with Group C unilateral retinoblastoma demonstrated dramatic tumor regression after two infusions of 5 mg of intra-arterial melphalan as primary therapy. Complete tumor control without recurrence was noted at 1 year. Retinal and choroidal perfusion was intact and the electroretinogram improved following therapy.
From the Ocular Oncology Service (NN, CLS, CGB, JAS), Wills Eye Institute, and the Department of Neurological Surgery (PMJ, RHR), Thomas Jefferson University, Philadelphia, Pennsylvania.
Supported by the Retina Research Foundation of the Retina Society in Cape Town, South Africa (CLS), and the Eye Tumor Research Foundation, Philadelphia, Pennsylvania (CLS).
The authors have no financial or proprietary interest in the materials presented herein.
Address reprint requests to Carol L. Shields, MD, Ocular Oncology Service, Suite 1440, Wills Eye Institute, 840 Walnut Street, Philadelphia, PA 19107. E-mail: firstname.lastname@example.org