Keratoconic eyes were successfully treated in a study with a combined treatment of collagen cross-linking and intrastromal corneal ring segment implantation coupled with intracorneal riboflavin injection.
“Intracorneal riboflavin injection into the tunnel was safe and may provide more penetration without epithelial removal,” the study authors said.
The non-comparative, retrospective case series evaluated the effectiveness of intracorneal riboflavin injection into the corneal channel with collagen cross-linking and Intacs (Addition Technology) implantation in 131 keratoconic eyes of 105 patients.
Patients were followed for a mean of 7 months after the procedure.
The mean improvement was 0.26 logMAR in uncorrected distance visual acuity and 0.24 logMAR in corrected distance visual acuity (both P < .05). Mean manifest spherical refraction decreased from –3.87 D to –1.25 D, while the mean manifest cylinder decreased from –3.89 D to –2.27 D, according to the study.
No intraoperative or postoperative complications were detected.