Prophylaxis with intracameral cefuroxime continues to prove effective in preventing endophthalmitis

  • February 15, 2010

BUDAPEST, Hungary — Results of a large retrospective series of patients in a single hospital unit confirm that the use of intracameral cefuroxime significantly lowers the incidence of endophthalmitis after cataract surgery.

Out of a total of 3,494 patients operated in the Ophthalmology Unit of the Royal Victoria Eye and Ear Hospital in Dublin, Ireland, between January 2007 and June 2009, only four were readmitted with suspect endophthalmitis, for a total suspected endophthalmitis rate of 0.11%.

"In our hospital, the incidence of presumed postoperative endophthalmitis before commencing the use of intracameral cefuroxime was 0.5%," Franciska Meszaros, MD, said at the winter meeting of the European Society of Cataract and Refractive Surgeons. "Using intracameral antibiotics reduced the suspected endophthalmitis rate by a factor of 4.5."

These data correlate well with the findings of the ESCRS study, she said.

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