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In the Journals Plus

Decline in cervical lesions driven by HPV vaccination

Niccolai LM, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix455.
Age and cohort patterns seen in recent data showed that declines in high-grade cervical lesions among young women are likely driven by HPV…
In the Journals Plus

Obesity, diabetes associated with increased risk for severe malaria infection

Wyss K, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix437.
Comorbidity, particularly diabetes, and obesity were significant risk factors for severe infection among nonimmune travelers and immigrants from…
In the Journals Plus

Low 25-(OH)D levels tied to poor glycemic control, more insulin use

Lim LL, et al. J Diabetes Investig. 2017;doi:10.1111/jdi.12696.
In adults with type 2 diabetes and chronic kidney disease, lower vs. higher levels of serum 25-hydroxyvitamin D were associated with poorer glycemic…
In the Journals Plus

Reduced-intensity, standard conditioning demonstrate comparable transplant outcomes in myelodysplastic syndrome

Kröger N, et al. J Clin Oncol. 2017;doi:10.1200/JCO.2016.70.7349.
Pulsipher MA. J Clin Oncol. 2017;doi:10.1200/JCO.2017.72.8048.
A reduced-intensity conditioning regimen yielded comparable RFS and OS as standard myeloablative conditioning among patients with myelodysplastic…
In the Journals Plus

High DHEAS increases early puberty risk in girls

Pereira A, et al. J Endocr Soc. 2017;doi:10.1210/js.2017-00120.
Girls with high dehydroepiandrosterone sulfate levels had an increased risk for early therlarche and early pubarche, whereas high…
In the Journals Plus

Ovarian volume, follicle excess tied to insulin resistance in PCOS

Hong S, et al. Clin Endocrinol. 2017;doi:10.1111/cen.13380.
Polycystic ovarian morphology was associated with insulin resistance in women with polycystic ovary syndrome, according to findings published in…
In the Journals Plus

Genetic screening, follow-up may decrease DKA at diabetes diagnosis

Hekkala AM, et al. Pediatr Diabetes. 2017;doi:10.1111/pedi.12541.
The frequency of diabetic ketoacidosis precipitating diagnosis of type 1 diabetes in children may be decreased with genetic screening and follow-up…
In the Journals Plus

Vitamin A deficiency linked with TB in household contacts of patients

Aibana O, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix476.
Findings published in Clinical Infectious Diseases indicated that vitamin A deficiency was strongly predictive of tuberculosis among Peruvians who
In the Journals Plus

Elevated glucose levels, diabetes may reduce risk for glioma

Schwartzbaum J, et al. Sci Rep. 2017;doi:10.1038/s41598-017-01553-2.
Researchers observed an inverse relationship between blood glucose levels and risk for glioma, according to an analysis of two study cohorts…
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Replacing sedentary time with physical activity reduces adiposity

Dalene KE, et al. Obes Sci Pract. 2017;doi:10.1002/osp4.114.
Replacing sedentary time with moderate physical activity may be effective in reducing waist circumference and BMI in younger children, whereas…
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Lenalidomide maintenance extends PFS in elderly patients with diffuse large B-cell lymphoma

Thieblemont C, et al. J Clin Oncol. 2017;doi:10.1200/JCO.2017.72.6984.
Lenalidomide maintenance prolonged PFS among elderly patients with diffuse large B-cell lymphoma who had achieved partial or complete response to…
In the Journals Plus

Neonatal vitamin D status not tied to childhood fracture

Händel MN, et al. Am J Clin Nutr. 2017;doi:10.3945/ajcn.116.145599.
Fracture risk in childhood does not seem to be affected by neonatal vitamin D status, according to findings published in the American Journal of
In the Journals Plus

Risk-adapted therapeutic strategies effective for early-stage Hodgkin lymphoma

Sasse S, et al. J Clin Oncol. 2017;doi:10.1200/JCO.2016.70.9410.
A risk-adapted strategy that intensifies combined-modality treatment in early-unfavorable Hodgkin lymphoma and reduces dosage for early-favorable…
In the Journals Plus

Genetic low BMI not associated with increased risk for Alzheimer’s disease

Nordestgaard LT, et al. J Clin Endocrinol Metab. 2017;doi:10.1210/jc.2017-00195.
In a study published in the Journal of Clinical Endocrinology and Metabolism, researchers from Denmark reported lifelong low BMI was not linked with
In the Journals Plus

At-risk migrants show high rates of TB after migration

Dobler CC, et al. Lancet Infect Dis. 2017;doi:10.1016/S1473-3099(17)30194-9.
Migrants who were at risk for tuberculosis demonstrated a high rate of disease after migration, suggesting that preventive treatment for latent
In the Journals Plus

Screen-detected breast cancers persist without treatment

Arleo EK, et al. J Am Coll Radiol. 2017;doi:10.1016/j.jacr.2017.01.038.
Screen-detected breast cancers that went untreated remained visible and suspicious for malignancy at next
In the Journals Plus

Hyperthyroidism increases death, CVD risk

Giesecke P, et al. Thyroid. 2017;doi:10.1089/thy.2017.0029.
Adults with hyperthyroidism may be at increased risk for death and cardiovascular disease compared with those without hyperthyroidism, according to…
In the Journals Plus

Study reveals microbiome of newly opened hospital

Lax S, et al. Sci Transl Med. 2017;doi:10.1126/scitransmed.aah6500.
A recent study illustrates how bacteria colonize and spread between patients, staff and surfaces within a newly constructed hospital. Researchers say…
In the Journals Plus

Insulin dose increase smaller with basal-bolus therapy vs. other regimens

Fujita N, et al. J Diabetes Investig. 2017;doi:10.1111/jdi.12693.
Adults with type 2 diabetes assigned to basal-bolus therapy require a smaller increase in insulin dose after 1 year compared with adults assigned to…
In the Journals Plus

HIV drugs raltegravir, efavirenz similar in AIDS, mortality outcomes

Cole SR, et al. Clin Infect Dis. 2017;doi:10.1093/cid/cix199.
A regimen containing the integrase inhibitor raltegravir yielded AIDS and overall mortality outcomes similar to one containing efavirenz in patients…