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Age-related clonal hematopoiesis increased risk for hematologic malignancies

November 26, 2014

Somatic mutations that led to clonal outgrowth of hematopoietic cells occurred more frequently in older patients and were associated with an increased risk for hematologic malignancies, according to results of two studies published in The New England Journal of Medicine.

The first analysis — conducted by Siddhartha Jaiswal, MD, PhD, clinical fellow in pathology at Massachusetts General Hospital, and colleagues — included 17,182 adults who were unselected for hematologic phenotypes (median age, 58 years). A majority of these participants (n=15,801) were enrolled in type 2 diabetes association studies, and 1,381 were enrolled in the Jackson Heart Study.

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VIDEO: Wound closure with new technologies

November 26, 2014
NEW YORK — At OSN New York, John A. Hovanesian, MD, discusses corneal wounds, leak rates and the challenges associated with wound closure and the use of hydrogel…
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VIDEO: Distinguishing asthma from COPD in elderly poses challenge to clinicians

November 26, 2014
ATLANTA — In this video, Stephen P. Peters, MD, PhD, FAAAAI, FCCP, FACP, FCPP, discusses his presentation on differentiating asthma from COPD in the aging…
Meeting News Coverage

Physical activity program did not prevent CV events in older adults

November 26, 2014
CHICAGO — A structured physical activity program had no effect on CV events in older adults compared with a health education program, according to new data from…
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In the Journals
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USPSTF finds insufficient evidence for universal vitamin D screening

November 26, 2014
The balance of benefits and harms of screening asymptomatic adults for vitamin D deficiency cannot be assessed based on…
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Blog Video

Phimotic capsular bag-IOL complex subluxation

November 18, 2014
Delayed capsular bag-IOL subluxation is often encountered in clinical practice, and it is a cause of concern to both…
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Meeting News Coverage Video
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VIDEO: Distinguishing asthma from COPD in elderly poses challenge to clinicians

November 26, 2014
ATLANTA — In this video, Stephen P. Peters, MD, PhD, FAAAAI, FCCP, FACP, FCPP, discusses his presentation on…
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