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Biologic therapy not cost-effective for RA after methotrexate fails

May 29, 2017

Initiating biologic therapy in patients with rheumatoid arthritis when methotrexate monotherapy fails increases costs substantially and provides minimal incremental benefit compared with triple therapy, according to data published in Annals of Internal Medicine.

The researchers suggest that triple therapy be used first before switching to a biologic strategy because it could reduce patients’ out-of-pocket costs and not expose them to serious side effects associated with biologic therapy.

In the Journals Plus

Decline in cervical lesions driven by HPV vaccination

May 28, 2017
Age and cohort patterns seen in recent data showed that declines in high-grade cervical lesions among young women are likely driven by HPV vaccination, not changes in…
In the Journals

Both HA and PRP linked with significantly improved pain relief in patients with knee OA

May 26, 2017
Patients with knee osteoarthritis who received either platelet-rich plasma or hyaluronic acid injections experienced a significant improvement in pain relief at early…
In the Journals

Racial residential segregation associated with systolic BP changes

May 26, 2017
A reduction in exposure to racial residential segregation was linked to lower systolic BP, according to a study in JAMA Internal Medicine. “Our study suggests…
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CME CNE CPE

Familial Chylomicronemia Syndrome: Cause, Effect, and Solutions to Improve Patients' Quality-of-Life

This activity is supported by an educational grant from Akcea Therapeutics™ A Subsidiary of Ionis Pharmaceuticals, Inc.
Endorsed by: The National Pancreas Foundation.

Familial chylomicronemia syndrome (FCS) is a rare and potentially life-threatening genetic disease. The clinical…
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GI Bookshelf

Question 37: Which Asymptomatic Patients With Cirrhosis Should Undergo An Upper Endoscopy To Determine Whether They Have Esophageal Varices?

From Curbside Consultation of the Liver: 49 Clinical Questions
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American Academy of Allergy, Asthma & Immunology Annual Meeting

American Academy of Allergy, Asthma & Immunology Annual Meeting

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VIDEO: Endoscopic bariatric therapies help GIs actively manage obesity

May 9, 2017
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