Infectious Disease

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APRI, FIB4 guide esophageal varices screening in light of hemophilia, coinfection

February 22, 2017

The aspartate transaminase-platelet ratio index and Fibrosis-4 score were effective non-invasive markers to monitor fibrosis and correlated to the presence of esophageal varices in hemophilic patients coinfected with HIV and hepatitis C, according to a new study.

“The use of such non-invasive and simple markers to check liver fibrosis is especially important in hemophilic patients, in whom liver biopsies should be avoided because of the possible hemorrhagic complication,” the researchers wrote. “It appears that APRI and FIB4 are good indicators for monitoring not only liver fibrosis but also esophageal varices, and we therefore strongly recommend that endoscopy be carried out when patients show an APRI or FIB4 value over the cut-off value described in this study.”

Meeting News

Phase 3 data find doravirine safe, effective for HIV-1 treatment

February 22, 2017
Merck recently announced the results of a phase 3 clinical trial that found doravirine, an investigational non-nucleoside reverse transcriptase inhibitor, was…
Meeting News

ACIP recommends single-dose revaccination for infants born to HBV-infected mothers

February 22, 2017
The Advisory Committee on Immunization Practices voted today in favor of single-dose alternative to 3-dose revaccination for infants born to hepatitis B surface…
In the Journals Plus

Small number of ‘superspreaders’ caused most Ebola infections, drove West Africa epidemic

February 22, 2017
Health officials could have prevented most cases of the 2014 Ebola virus outbreak by finding and quarantining a tiny percentage of patients, according to a study…
In the Journals

Risk for autism linked to herpes infection in pregnant women

February 22, 2017
Pregnant women with an active case of genital herpes were twice as likely to have a child diagnosed with autism spectrum disorder, according to a study that recently…
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CME

Operation Immunization 2016: Enhancing HPV Immunization

This activity is supported by an educational grant from Merck & Co., Inc.

During the last decade, several new vaccines, including the meningococcal conjugate (MCV4), tetanus, diphtheria…
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Perspective

IDSA guidelines address health care–associated ventriculitis, meningitis

February 21, 2017
The Infectious Diseases Society of America has released new guidelines on detecting and treating ventriculitis and…
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Featured
Conference on Retroviruses and Opportunistic Infections (CROI)

Conference on Retroviruses and Opportunistic Infections (CROI)

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Meeting News

VIDEO: CROI 2017 Overview

February 14, 2017
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