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HCV RNA in liver explants does not lead to HCV recurrence post-transplant

April 27, 2015

VIENNA — The presence of hepatitis C virus infection RNA in liver explants did not correlate with a likelihood of hepatitis C recurrence after liver transplantation, according to study results presented at the 2015 International Liver Congress.

“Hepatitis C recurrence is universal in patients with detectable HCV RNA at time of liver transplantation,” Martina Gambato, MD, Liver Unit, University of Barcelona, Spain, said during her presentation. “Due to the high efficacy and good safety profile of direct-acting antivirals, most patients awaiting [liver transplant] will undergo antiviral therapy. Residual HCV RNA in the liver explants has been previously shown to be associated to HCV recurrence in patients treated with [pegylated interferon and ribavirin] on the waiting list.”

Gregory Demuri Meeting News Coverage

Bacterial densities of S. pneumoniae, H. influenzae increase during sinusitis

April 26, 2015
SAN DIEGO — Bacterial densities of Streptococcus pneumoniae and Haemophilus influenzae increased during episodes of acute bacterial sinusitis, according to data…
ANRS CO23 CULPIT: Sovaldi, daclatasvir well tolerated in transplant, recurrence Meeting News Coverage

ANRS CO23 CULPIT: Sovaldi, daclatasvir well tolerated in transplant, recurrence

April 26, 2015
VIENNA — Regimens containing Sovaldi and daclatasvir were efficacious and well tolerated in a cohort of patients with recurrence of hepatitis C virus after liver…
Meeting News Coverage

ALLY-1: transplant patients, those with cirrhosis achieve SVR12 with daclatasvir, sofosbuvir

April 26, 2015
VIENNA — A regimen containing Sovaldi and daclatasvir was associated with favorable 12-week sustained virologic response rates in a cohort of patients with…
Meeting News Coverage

Oligonucleotide injection reduced HCV viral load

April 26, 2015
VIENNA — Injection of an oligonucleotide with activity against microRNA-122 led to undetectable viral load in a cohort of HCV patients of multiple genotypes…
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CME
Regimen Selection in HIV

Regimen Selection in HIV: Considering New Options to Optimize Outcomes
Monograph

This activity is supported by an educational grant from Gilead Sciences Medical Affairs.

More than 2 decades into the antiretroviral therapy (ART) era, numerous options are available for HIV treatment. The…
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Meeting News Coverage Video
VIDEO: Effectiveness of inactivated vs. live flu vaccine currently unclear

VIDEO: Effectiveness of inactivated vs. live flu vaccine currently unclear

April 24, 2015
BETHESDA, Md. — Richard K. Zimmerman, MD, of the University of Pittsburgh, explains the results of his study…
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CME
HCV VOICE

HCV VOICE II: Optimizing Virological Outcomes with Integrated HCV Education

This activity is supported by an educational grant from Janssen Therapeutics, Division of Janssen Products, LP.

Chronic hepatitis C virus (HCV) infection is a leading cause of cirrhosis, end-stage liver disease, hepatocellular…
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