Infectious Disease

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FDA issues PML warning for MS patients taking Gilenya

August 4, 2015

Following reports of progressive multifocal leukoencephalopathy among patients taking Gilenya for multiple sclerosis, the FDA has issued a warning of possible infection for those prescribed the immunosuppressant drug.

Gilenya (fingolimod, Novartis) is an immunomodulator used to treat patients with relapsing forms of multiple sclerosis (MS). In 2013, a patient was reported to have developed progressive multifocal leukoencephalopathy (PML) after taking the drug; however, no conclusive link could be made due to previous treatment with multiple courses of IV corticosteroids and another immunosuppressant drug known to cause the infection.

Janssen initiates phase 1 trial of Olysio/odalasvir for AL-335 pharmacokinetics

August 4, 2015
Janssen Pharmaceutical Companies has initiated a phase 1 clinical trial that will evaluate the effect of Olysio and odalasvir on the pharmacokinetics of AL-335, a…
In the Journals

Compliance with infection control guidelines poor; worse in low-income countries

August 4, 2015
Compliance with recommended infection control guidelines in low- and middle-income countries is substandard, with opportunity for improvement in hospitalwide…
Timothy J. Kidd In the Journals

Patient movement increases risk for transferring P. aeruginosa infection in cystic fibrosis

August 4, 2015
The movement of patients within cystic fibrosis centers appeared likely to be an important risk factor for the acquisition of shared P. aeruginosa strain infections…
Samir Shah In the Journals

Residence predicts pediatric hospitalizations for bronchiolitis, pneumonia

August 4, 2015
A child’s home address in a low socioeconomic status area was predictive of future bronchiolitis or pneumonia hospitalization, according to recent study…
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CME
Infectious Disease Case Consults

The Patient with Acute-Bacterial Skin and Skin-Structure Infections

No commercial support for this activity.

This CME activity will focus on the diagnosis and management of patients with acute-bacterial skin and skin-structure…
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At Issue Video
VIDEO: Cure is ‘next frontier’ of HIV

VIDEO: Cure is ‘next frontier’ of HIV

July 1, 2015
Timothy Brown – the Berlin patient – has led researchers to the next frontier of HIV research, according to…
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CME
Conjuctivitis

Management of Pediatric Conjunctivitis and Otitis/Conjunctivitis Syndrome

This activity is supported by an educational grant from Alcon Research, LTD.

Acute bacterial conjunctivitis affects approximately 1 of every 8 children each year, and 5 million cases occur in the…
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