December 18, 2014
Neurocognitive performance did not appear to be associated with HCV coinfection among people with HIV, according to recently published data.
David B. Clifford, MD, of Washington University School of Medicine, and colleagues administered neurocognitive performance tests to 1,582 HIV patients enrolled in the CNS HIV Antiretroviral Therapy Effects Research study. Test results were compared between participants who were HCV-seropositive (n=408) and HCV-seronegative (n=1,174), as well as within a subset of seropositive (n=160) and seronegative (n=707) participants without serious comorbid neurologic conditions. Factors associated with HIV, demographics and liver function also were considered.