Nosocomial Infections

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Multidrug resistant gram-negative infections increased 700% among children

March 15, 2017

The number of children infected with multidrug resistant gram-negative enteric Enterobacteriaceae increased significantly over the previous 8 years, associated with longer hospital stays and increased mortality risk, according to a recent study.

“There is a clear and alarming upswing throughout this country of antibiotic-resistant Enterobacteriaceae infections in kids and teens,” Sharon B. Meropol, MD, PhD, from the department of pediatrics at Case Western Reserve University, said in a press release. “This makes it harder to effectively treat our patients’ infections. The problem is compounded because there are fewer antibiotics approved for young people than adults to begin with. Health care providers have to make sure we only prescribe antibiotics when they are really needed.”

At Issue

What caused C. auris to emerge on several continents around the same time?

Infectious Disease News, March 2017
The earliest known strain of Candida auris dates back to 1996 in South Korea, according to the CDC. However, research suggests the fungal pathogen emerged independently…
Cover Story

C. auris: ‘A nasty bug’ threatening US hospitals

Infectious Disease News, March 2017
Last June, the CDC issued a clinical alert to health care facilities in the United States about Candida auris, an emerging and often drug-resistant fungus with a high…
In the Journals Plus

Higher bacterial burden increases E. coli transmission odds

March 14, 2017
As Escherichia coli bacterial counts increased on one health care worker’s hand, so did the extent of transmission to another in a recent study. The results of…
CME

HCV Updates and Case Challenges for the Rapidly Changing Landscape

This activity is supported by an educational grant from Merck & Co., Inc.

In the past few years, significant progress has been made in the treatment of chronic hepatitis C virus (HCV). Highly…
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Perspective

Letermovir effective as prophylaxis for cytomegalovirus in high-risk hematopoietic cell transplant patients

February 22, 2017
Letermovir was highly effective in a phase 3 trial at preventing infection with cytomegalovirus, or CMV, in patients…
More »
Featured
Conference on Retroviruses and Opportunistic Infections (CROI)

Conference on Retroviruses and Opportunistic Infections (CROI)

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Meeting News Coverage

VIDEO: National learning health system can improve infection prevention, routine care

October 8, 2015
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In the Journals PlusAbstract Only

Ralstonia mannitolilytica infections in an oncologic day ward: description of a cluster among high-risk patients

March 20, 2017
AUTHORS:
Lucarelli C, et al.

In the Journals

Multidrug resistant gram-negative infections increased 700% among children

March 15, 2017
The number of children infected with multidrug resistant gram-negative enteric Enterobacteriaceae increased significantly over the previous 8 years…

At Issue

What caused C. auris to emerge on several continents around the same time?

Infectious Disease News, March 2017
The earliest known strain of Candida auris dates back to 1996 in South Korea, according to the CDC. However, research suggests the fungal pathogen…

Cover Story

C. auris: ‘A nasty bug’ threatening US hospitals

Infectious Disease News, March 2017
Last June, the CDC issued a clinical alert to health care facilities in the United States about Candida auris, an emerging and often drug-resistant…

In the Journals Plus

Higher bacterial burden increases E. coli transmission odds

March 14, 2017
As Escherichia coli bacterial counts increased on one health care worker’s hand, so did the extent of transmission to another in a recent…

In the Journals PlusAbstract Only

Management of a cluster of Clostridium difficile infections among patients with osteoarticular infections

March 13, 2017
AUTHORS:
Färber J, et al.

In the Journals Plus

Researchers track spread of multidrug-resistant bacteria in hospital sinks

March 11, 2017
Researchers investigating how multidrug-resistant bacteria can potentially spread from hospital sinks to patients found that bacteria in sinks…

In the Journals

Infective endocarditis less common with Sapien device after percutaneous valve implantation

March 9, 2017
Infective endocarditis appeared to be less common after percutaneous pulmonary valve implantation with the Sapien pulmonic transcatheter heart valve…

In the Journals PlusPerspective

Hospital floors a greater source of infection than previously thought

March 7, 2017
The floors of patient rooms in hospitals are often contaminated with health-care associated pathogens, suggesting that hospital floors may pose a

Perspective

Letermovir effective as prophylaxis for cytomegalovirus in high-risk hematopoietic cell transplant patients

February 22, 2017
Letermovir was highly effective in a phase 3 trial at preventing infection with cytomegalovirus, or CMV, in patients who underwent allogeneic…

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