Infectious Disease News


The following articles appeared in the print edition of INFECTIOUS DISEASE NEWS.

Table of Contents

FDA launches Expedited Access Pathway program for devices

Gilead submits NDA for HIV combination therapy candidate

Microneedle patch could increase measles vaccinations

Date syrup contains antibacterial compounds

CRE outbreaks draw focus on ERCP, device-related infections

CDC enrolling 6,000 Sierra Leone HCWs in Ebola vaccine trial

Australia to end welfare payments for families rejecting vaccination

CDC helps African Union launch African CDC

Cover Story

Global rise in dengue warrants improved prevention, control methods


Novel mechanism and potential treatment strategies for CVD in HIV patients

Steven K. Grinspoon, MD

Eye on ID

Syphilis: An old, easily diagnosed and treated disease … on the rise

Matthew E. Levison, MD; Donald Kaye, MD

FDA News

FDA grants new breakthrough therapy designations for grazoprevir/elbasvir

FDA grants priority review for oral, interferon-free treatment of HCV genotype 4

In the Journals

Model accurately predicts rapid response in HCV at 4 weeks

N. lactamica may suppress meningococcal outbreaks

Molecular switch deactivates HCMV; may benefit organ transplantation

MRSA infections linked with prior nasal colonization at VA hospital

Newer HCV medications yield health benefits at more reasonable cost

More than 90% of hand hygiene opportunities missed during anesthetic procedures

HIV self-testing may be cost-effective in low-income countries

HIV infections surge in Indiana

HIV accelerates development of age-related illnesses

Hospitalization rates for pediatric osteoarticular infections rise

Kidney transplant survival rate found worse in recipients with HCV vs. HIV

Iron increases malaria risk during pregnancy

In utero exposure to Retrovir linked to congenital heart defects

Nitrofurantoin less effective than other antibiotics for UTI patients

Routine rotavirus vaccine reduced disease circulation in US children

Simpler forecasting models do not account for variability, uncertainty

Ribotype 027 increases risk for severe C. difficile infection, mortality

Rise in health data breaches driven by criminal activity

Text messages track adverse events after flu vaccine in HCP

US affected by widespread antibiotic shortages from 2001-2013

Some weight gain after starting ART may reduce mortality

T-cell biomarkers distinguish active, latent M. tuberculosis infection

Online content for Ebola exceeds suggested reading levels

Oral antibiotics showed similar efficacy, safety to injectable antibiotics for bacterial infections

Validated risk score for CKD may guide HIV treatment decisions

Novel syphilis test distinguishes active vs. past infections

Portable mass spectrometry technique accurately detects C. difficile in unprocessed stool

Respiratory virus infection before HCT increases mortality

Persistent H. pylori in childhood linked to specific strain profiles, future disease

Point-of-care fingerstick CRAG provides low-cost, rapid meningitis diagnosis

Campylobacteriosis outbreak linked to undercooked chicken livers

C. difficile cases highest in Northeast, springtime

Abnormalities related to C. gattii may be slow to resolve

Diagnostic tool may help risk-stratify suspected Ebola cases

CRISPR system opens window to C. albicans pathology

Bundled TB testing, on-site provider training improves disease detection, outcomes

Antimicrobial stewardship program reduces antibiotic use

Amoxicillin/probenecid effectively treats syphilis in HIV patients

Azithromycin ineffectively treats macrolide-resistant M. genitalium

BSTI testing rates low among sexually active HIV population

Beta-lactam performs similarly to preferred treatments for CAP

Duodenoscopes cause of E. coli outbreak in Washington

Few mutations implicated in transmission of drug-resistant HIV

High blood pressure more common than previously believed in children with HIV

Exposure to bleach increases risk for respiratory infections

Flu vaccine did not modify flu severity during 2012-2013 season

Group therapy improves depression outcomes among adults with HIV

Environment less important in hospital transmission of CRE

Meeting News Coverage

ANRS CO22: SVR4 rates near 100% for sofosbuvir/daclatasvir in genotype 1

Providers need to continually promote HPV vaccine to parents

HBV vaccine unaffected by diabetes

EASL releases, outlines 2015 HCV recommendations

Tdap appears safe for pregnant women, infants

RUBY-I: Preliminary study shows safety of 3D + ribavirin in CKD

C-EDGE: Grazoprevir/elbasvir regimen yields high SVR rates in patients with HCV

Chikungunya common among US volunteers in Dominican Republic

C-SALT: Child-Pugh B patients respond to grazoprevir/elbasvir

U.K. residents swimming in coastal waters may ingest resistant E. coli

Prompt contact tracing disrupts Ebola virus transmission into Senegal

Previous treatment failures respond to 24 weeks of Harvoni

Tour bus surveillance identifies potential norovirus cases at Yellowstone

Pharmacology Consult

Beyond ART: Primary care pharmacotherapy for people living with HIV

Leah Molloy, PharmD