LONDON A national mandatory policy of screening
all elective and emergency hospital admissions for methicillin-resistant
Staphylococcus aureus did not appear cost-effective. Further research
examining sensitivity to model parameters, setting and long-term effects is
currently under way, according to Julie Robotham, PhD.
Targeted screening of high-risk specialties
appears at this preliminary stage more likely to be cost-effective, reflecting
the higher proportion of infections seen, Robotham, of the Health
Protection Agency in London, told Infectious Disease News.
Robotham and colleagues collected data from a national
1-week audit of MRSA admission screening in 144 National Health System
hospitals. They used this data to develop an MRSA transmission model to
evaluate the effectiveness and cost-effectiveness of 10 different screening and
The health benefits of all strategies were similar. When
compared with no screening, intensive screening strategies reduced MRSA
infection rates by up to 20%, but there was a less than 5% reduction in
When looking at cost, the researchers found that
screening of admissions to high-risk specialties had cost per quality-adjusted
life years value beneath the usual National Health Service willingness-to-pay
- Robotham J. #LB2808. Presented at: 22nd European Congress of
Clinical Microbiology and Infectious Diseases; March 31-April 3, 2012; London.
- Dr. Robotham reports no relevant financial disclosures.