Adolescents with HIV at risk for being lost to follow-up after 18th birthday

  • July 30, 2012

Youth with HIV have an increased risk for being lost to follow-up after the age of 18 years, according to data from a poster presented at the XIX International AIDS Conference.

“Given the challenges of young adulthood, youth with HIV infection do appear to be at risk for falling out of care,” Allison Agwu, MD, assistant professor of pediatrics at Johns Hopkins Medical Institutions, told Infectious Disease News. “These youth may be seen at adult or pediatric/adolescent clinics, and there may be factors intrinsic to the different clinical programs at those sites that may impact whether or not they stay in care.”

Agwu and colleagues analyzed factors associated with loss to follow-up among those who turned 18 years of age from 2002 to 2008. The adolescents with HIV were receiving care at one of 13 clinics in the HIV Research Network cohort. This study included 120 adolescents who were receiving care before aged 18 years.

Twelve of the 120 adolescents had no outpatient follow-up after their 18th birthday, but none of the adolescents lost to follow-up died. Gender, insurance status, CD4 count and ART prescription did not differ between adolescents lost to follow-up and those remaining in care. After adjusting for gender, race/ethnicity, outpatient visits, HIV acquisition risk and insurance status, receiving care at an adult site in adolescence was associated with loss to follow-up care.

“As providers caring for this population, we need to be creative about the mechanisms to engage and maintain youth in care, such as text messaging and flexible appointment hours, among others,” Agwu said. “Importantly, we need to pay attention and have programs in place to follow, track and re-engage when they do fall out of care.”

References:

Agwu A. #MOPE61. Presented at: XIX International AIDS Conference; July 22-27, 2012; Washington, D.C.

Disclosures:

Dr. Agwu reports no relevant financial disclosures.

Perspective
Michael T. Brady, MD

Michael T. Brady

  • Adolescents with chronic diseases, including HIV infection, present challenges concerning optimal site of care as they age. Eventually a formal transition plan will be required. In this study, the researchers assessed the maintenance of medical care in adolescents who had reached age 18 years. Of the 120 HIV-infected 18-year-olds, 12 did not receive any care after their 18th birthday. There were no obvious demographic differences, eg, race, ethnicity, and route of HIV requisition, between those who did or did not continue to receive medical care. However, 75% of those who fell out of care vs. 31% of those who remained in care had been transitioned to an adult HIV care site. Retention in care of older HIV-infected adolescents would be improved if structural and programmatic differences between adult and pediatric care sites are assessed to determine which factors seem to be most important in maintaining the health care relationship.
    • Michael T. Brady, MD
    • Chairman, AAP Committee on Infectious Diseases
      Children’s Hospital Columbus

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