Antimicrobials

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Piperacillin not associated with adverse events among neonates

Piperacillin not associated with adverse events among neonates
May 24, 2017

No statistically significant connections between piperacillin and adverse events, such as seizures and rashes, in infants were observed in a study of drug exposure outcomes from a national electronic health record database.

“Evaluating drug safety in infants is challenging for several reasons. Performing trials with an adequate number of infants to assess drug safety requires considerable time and resources,” Sara Salerno, PharmD, from the UNC Eshelman School of Pharmacy, and colleagues wrote. “Using electronic health record data from national databases can be a suitable approach to evaluate drug safety in infants since it can overcome many of these limitations of traditional clinical trials.”

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Nearly one in four adult outpatients with CAP fail antibiotic therapy

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‘Handshake stewardship’ reduced hospital antimicrobial use by almost 11%

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Rather than preauthorizing antibiotics or imposing restriction policies, an antibiotic stewardship program in which a team of pharmacists and physicians evaluated all…
Perspective

IDSA outlines trial designs for development of antibacterial agents

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A white paper published on behalf of the Infectious Diseases Society of America, or IDSA, outlined new trial designs for the timely development and approval of…
CME CNE CPE

Familial Chylomicronemia Syndrome: Cause, Effect, and Solutions to Improve Patients' Quality-of-Life

This activity is supported by an educational grant from Akcea Therapeutics™ A Subsidiary of Ionis Pharmaceuticals, Inc.
Endorsed by: The National Pancreas Foundation.

Familial chylomicronemia syndrome (FCS) is a rare and potentially life-threatening genetic disease. The clinical…
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In the Journals Plus

Early administration of prophylaxis does not significantly reduce surgical site infections

May 2, 2017
Early administration of surgical antimicrobial prophylaxis did not significantly reduce the risk for surgical site
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Featured
Conference on Retroviruses and Opportunistic Infections (CROI)

Conference on Retroviruses and Opportunistic Infections (CROI)

Video
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VIDEO: ID support in ASPs has larger impact on antibiotic use

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In the Journals

Piperacillin not associated with adverse events among neonates

May 24, 2017
No statistically significant connections between piperacillin and adverse events, such as seizures and rashes, in infants were observed in a study of…

Meeting News

Nearly one in four adult outpatients with CAP fail antibiotic therapy

May 21, 2017
Approximately one in four adult outpatients prescribed antibiotic therapy for community-acquired pneumonia did not adequately respond to treatment…

In the Journals

‘Handshake stewardship’ reduced hospital antimicrobial use by almost 11%

May 19, 2017
Rather than preauthorizing antibiotics or imposing restriction policies, an antibiotic stewardship program in which a team of pharmacists and…

Perspective

IDSA outlines trial designs for development of antibacterial agents

May 17, 2017
A white paper published on behalf of the Infectious Diseases Society of America, or IDSA, outlined new trial designs for the timely development and…

In the Journals Plus

Automated intervention improves care for S. aureus bacteremia

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An automated intervention increased the number of infectious disease consultations and improved targeted antimicrobial therapy and adherence to

Editorial

Health IT resources are mandatory for effective antimicrobial stewardship programs

Infectious Disease News, May 2017
Debra A Goff, PharmD, FCCP
Approximately 700,000 people die every year from antibiotic-resistant infections, and this number is projected to surpass 10 million per year by…

FDA News

FDA updates warnings on oral, injectable fluoroquinolones

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In the Journals Plus

Appropriate therapy reduces mortality in bloodstream infections due to carbapenemase-producing Enterobacteriaceae

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Appropriate therapy was protective against mortality among patients with bloodstream infections due to carbapenemase-producing Enterobacteriaceae

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Fluoroquinolone use associated with increased risk for carpal tunnel syndrome

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