Infectious Disease

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Miltefosine may serve as first-line treatment for leishmaniasis

February 8, 2016

Miltefosine was well-tolerated and effectively treated complicated Old World cutaneous and mucosal leishmaniasis, making it an ideal first-line treatment option, according to findings published in Open Forum Infectious Diseases.

There are four compounds that currently are available to treat leishmaniasis, a parasitic disease transmitted through bites of infected sand flies, according to the CDC. The compounds include parenterally administered pentavalent antimonial and amphotericin B, and orally administered fluconazole and miltefosine. Due to a lack of clinical trials comparing the efficacy of the agents, physicians typically assign treatment regimens based on personal experience, drug availability and cost, according to Vincent Mosimann, MD, from the Swiss Tropical and Public Health Institute, and colleagues.

CDC recognizes National Black HIV/AIDS Awareness Day 2016

February 7, 2016
National Black HIV/AIDS Awareness Day is recognized annually on Feb. 7 to raise awareness of HIV/AIDS and reduce the disproportionate impact of the infection on blacks…
In the Journals

Eradication plan reduces poliovirus in Nigeria

February 6, 2016
The installation of several public health innovations has increased progress toward the eradication of poliovirus within Nigeria and its neighboring countries, according…
In the Journals

Rapidly waning Tdap offers little long-term protection against pertussis

February 5, 2016
Tdap vaccine waned rapidly and provided only limited, short-term protection against pertussis when administered to adolescents as a booster for DTaP, according to recent…
In the Journals

CDC updates guidelines to prevent sexual transmission of Zika

February 5, 2016
Men who have traveled to an area with ongoing Zika virus transmission should consider abstaining from having sex with their pregnant partners or should…
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CME

Evolution of HIV Treatment: How to Start, How to Switch, How to Treat HIV/HCV Co-infection

This activity is supported by an educational grant from Gilead Sciences Medical Affairs.

Improvements in antiretroviral therapy (ART) continue to be made with the development of simplified, single-tablet…
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Video

VIDEO: Providers must be vigilant about screening for other STDs

December 15, 2015
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CME

Evolution of HIV Treatment: How to Start, How to Switch, How to Treat HIV/HCV Co-infection

This activity is supported by an educational grant from Gilead Sciences Medical Affairs.

Improvements in antiretroviral therapy (ART) continue to be made with the development of simplified, single-tablet…
More »