‘Gene surgery’ effectively removes HIV-1 from human cells

  • July 29, 2014

PHILADELPHIA — Temple University researchers have successfully eradicated latent HIV-1 virus from cultured human cells using a combination of molecular tools. Kamel Khalili, PhD, professor and chair of the department of neuroscience at Temple, and colleagues developed a technique of using guide RNA and a DNA-snipping enzyme, Cas9, to locate and excise the viral genome from human DNA. Once free of HIV-1, the cells will begin to self repair.

Khalili notes that the findings are a proof-of-concept and the approach is not ready for clinical practice, but the effective removal of HIV-1 from human cells constitutes a possible step towards a permanent cure for AIDS.

Full Story »

Personalize your page!

Register for Healio to get content tailored to your specialty and areas of interest. It’s FREE and only takes one minute. Register now!

More »
More »
More »
More »
More »
More »