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Antivirals improve CMV pneumonia outcomes after HCT

March 30, 2015

Outcomes of cytomegalovirus pneumonia after hematopoietic cell transplantation have improved modestly over the past 25 years largely due to antiviral treatment and changes in transplantation protocols rather than the use of adjunctive immunoglobulin treatment, according to recent findings.

“Although the development of effective cytomegalovirus (CMV) prevention strategies has significantly reduced the need to treat established CMV disease after hematopoietic cell transplantation (HCT), the management of CMV pneumonia remains a formidable challenge,” the researchers wrote. “Furthermore, late CMV disease may occur after both myeloablative and non-myeloablative HCT.”

In the Journals

Alcoholic hepatitis prevalent in patients with cirrhosis, GI bleeding

March 30, 2015
Alcoholic hepatitis was prevalent in patients with gastrointestinal bleeding, and alcoholic cirrhosis, but survival was similar with and without gastrointestinal…

Experts discuss whether shift in Medicare will reduce costs, improve quality of care

March 30, 2015
In response to concerns over Medicare’s current fee-for-service payment system, the Obama administration announced in January that by 2018 Medicare instead will…
In the Journals

HIV replicates in brain, CNS shortly after infection

March 30, 2015
HIV may begin replicating within a patient’s brain and central nervous system as soon as 4 months after infection, according to data recently published in PLoS

APIC commends researcher for hand hygiene study

March 29, 2015
Jorge Parada, MD, epidemiologist and medical director at Loyola University Health System, will be honored by the Association for Professionals in Infection Control…
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Regimen Selection in HIV: Considering New Options to Optimize Outcomes

This activity is supported by an educational grant from Gilead Sciences Medical Affairs.

More than two decades into the antiretroviral therapy (ART) era, there are numerous options for HIV treatment. The goal…
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Video: NIAID Ebola vaccine well tolerated, immunogenic

March 23, 2015
WILMINGTON, Del. — Julie Ledgerwood, DO, of the National Institute of Allergy and Infectious Diseases' Vaccine…
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Management of Pediatric Conjunctivitis and Otitis/Conjunctivitis Syndrome

This activity is supported by an educational grant from Alcon Research, LTD.

Acute bacterial conjunctivitis affects approximately 1 of every 8 children each year, and 5 million cases occur in the…
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