Infectious Disease

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Baraclude safely reduces HBV DNA among children, adolescents

February 8, 2016

In a randomized phase 3 study, children and adolescents with chronic hepatitis B virus infection treated with Baraclude showed reduced infection compared with children treated with placebo, according to published findings.

Researchers randomly assigned 180 treatment-naive children and adolescents to a regimen of Baraclude (entecavir, Bristol-Myers Squibb; n = 120) or placebo (n = 60) for a duration of 48 weeks. The primary endpoint of the study was hepatitis B e antigen (HBeAg) seroconversion and reduced HBV DNA levels (less than 50 IU/mL) at 48 weeks. Follow-up was through 96 weeks.

In the Journals

Oregon teen’s death linked to rare measles complication

February 8, 2016
The Oregon Health Authority reported that the 2015 death of a boy aged 14 years was the result of subacute sclerosing panencephalitis, a rare but fatal complication of…
In the Journals

Miltefosine may serve as first-line treatment for leishmaniasis

February 8, 2016
Miltefosine was well-tolerated and effectively treated complicated Old World cutaneous and mucosal leishmaniasis, making it an ideal first-line treatment option…

CDC recognizes National Black HIV/AIDS Awareness Day 2016

February 7, 2016
National Black HIV/AIDS Awareness Day is recognized annually on Feb. 7 to raise awareness of HIV/AIDS and reduce the disproportionate impact of the infection on blacks…
In the Journals

Eradication plan reduces poliovirus in Nigeria

February 6, 2016
The installation of several public health innovations has increased progress toward the eradication of poliovirus within Nigeria and its neighboring countries, according…
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CME

The Patient with Norovirus Infection

No commercial support for this activity.

Norovirus is highly contagious, highly persistent and often remains present after disinfection. This educational…
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Video

VIDEO: Discussion of HIV prevention strategies generates ‘enthusiasm and excitement’

December 15, 2015
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CME

The Patient with Conjunctivitis

No commercial support for this activity.

This CME activity will focus on the diagnosis and management of patients with conjunctivitis.
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