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Gilead submits NDA for HIV combination therapy candidate

April 18, 2015

Gilead Sciences has submitted a new drug application to the FDA for an investigational therapy for the treatment of HIV, according to a press release.

The company’s combination therapy includes two doses of emtricitabine and tenofovir alafenamide (F/TAF), the release said, and is intended for the management of HIV-1 in patients aged 12 years and older. A 200 mg/25 mg-dose is recommended; however, 200 mg/10 mg F/TAF is recommended when combined with a protease inhibitor plus ritonavir or cobicistat.

In the Journals

Online content for Ebola exceeds suggested reading levels

April 17, 2015
Information on the Ebola virus posted on public health agency websites is written above the recommended reading level, according to recent findings. Researchers from…
In the Journals

Beta-lactum performs similarly to preferred treatments for CAP

April 17, 2015
Patients with community-acquired pneumonia had similar outcomes when randomized to one of three antibiotic treatment therapies, with regard to 90-day mortality…
James Brien What's Your Diagnosis?Publication Exclusive

Erythema, swelling near the eye in a 6-week-old female

Infectious Diseases in Children, April 2015
James H. Brien, DO
A 6-week-old female presents with the sudden-onset of erythema and swelling near the left eye. The area was noted the day before to be a bit swollen, with the lids of…
In the Journals

CRISPR system opens window to C. albicans pathology

April 17, 2015
Massachusetts researchers have developed a CRISPR-Cas system that allows them to systematically edit the Candida albicans genome, which could lead to new antifungal…
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CME
HCV VOICE

HCV VOICE II: Optimizing Virological Outcomes with Integrated HCV Education

This activity is supported by an educational grant from Janssen Therapeutics, Division of Janssen Products, LP.

Chronic hepatitis C virus (HCV) infection is a leading cause of cirrhosis, end-stage liver disease, hepatocellular…
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Meeting News Coverage Video
VIDEO: Too soon to encourage vaccination in US by withholding state assistance

VIDEO: Too soon to encourage vaccination in US by withholding state assistance

April 15, 2015
BETHESDA, Md. — Walter A. Orenstein, MD, professor of medicine and associate director of the Emory Vaccine Center at…
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CME
Conjuctivitis

Management of Pediatric Conjunctivitis and Otitis/Conjunctivitis Syndrome

This activity is supported by an educational grant from Alcon Research, LTD.

Acute bacterial conjunctivitis affects approximately 1 of every 8 children each year, and 5 million cases occur in the…
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