Infectious Disease

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FIB-4, race predicts ESLD in HIV/HCV coinfected patients

July 29, 2015

The Fibrosis-4 score and race were useful in quantifying the risk for end-stage liver disease among patients with both HIV and hepatitis C virus, according to recent findings.

In the retrospective cohort study, researchers evaluated 6,016 HIV/HCV coinfected individuals on ART who were enrolled in the Veterans Aging Cohort Study (VACS) from January 1997 to Sept. 30, 2010. To identify potential predictors of end-stage liver disease (ESLD), the researchers assessed baseline variables such as FIB-4, aspartate aminotransferase-to-platelet ratio index (APRI), BMI, severe anemia, CD4 cell count, HIV RNA greater than 400 copies/mL, alcohol dependence or abuse, diabetes mellitus, hepatitis B coinfection and race among the patients. Study follow-up commenced after 1 year of ART. The primary endpoint was ESLD, which was delineated as hepatic decompensation, hepatocellular carcinoma or liver-associated mortality.

In the Journals

Nasopharyngeal bacteria, respiratory viruses linked to acute respiratory infection symptoms

July 29, 2015
Previously unexplained acute symptoms of respiratory tract infection in pediatric outpatients may be associated with respiratory viruses and nasopharyngeal bacteria…
In the Journals

Infection prevention methods in US vary after cesarean delivery

July 29, 2015
A survey of U.S. academic centers revealed marked variability in the practices used to prevent infections after cesarean delivery.“Additional clinical trials and…
In the Journals

Adults with diabetes more likely to contract TB

July 28, 2015
Adults with diabetes are up to seven times more likely to contract tuberculosis than the general population, even in countries with a low burden of the infectious…
In the Journals

Research on underexamined animal infections benefits human health

July 28, 2015
Just 10 diseases accounted for approximately half of all published research on wildlife-to-livestock infections in the past century, according to data in Proceedings of
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CME
Conjuctivitis

Management of Pediatric Conjunctivitis and Otitis/Conjunctivitis Syndrome

This activity is supported by an educational grant from Alcon Research, LTD.

Acute bacterial conjunctivitis affects approximately 1 of every 8 children each year, and 5 million cases occur in the…
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At Issue Video
VIDEO: Cure is ‘next frontier’ of HIV

VIDEO: Cure is ‘next frontier’ of HIV

July 1, 2015
Timothy Brown – the Berlin patient – has led researchers to the next frontier of HIV research, according to…
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CME
Infectious Disease Case Consults

The Patient with Hepatitis C

No commercial support for this activity.

This CME activity will focus on the diagnosis and management of patients with hepatitis C.
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