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Researchers explain origins of remaining groups of HIV-1

March 4, 2015

The origin of the last two phylogenetic lineages of HIV-1 have been traced to western lowland gorillas in southern Cameroon, according to recent findings published in Proceedings of the National Academy of Sciences.

HIV-1 has jumped species to humans on four separate occasions, producing groups M, N, O and P. Genetically closely related relatives of group M, which is responsible for the global AIDS pandemic, as well as group N, which has only been detected in a handful of people, have been identified in chimpanzees in southern Cameroon. However, until recently, the origins of groups O and P were unknown.

In the Journals

Serum TSH may be a marker in predicting ACLF severity, mortality

March 4, 2015
In a cohort of patients with hepatitis B virus infection-related acute–on-chronic liver failure, thyroid stimulation hormone level was a useful indicator for…
Oral swabs show potential in TB detection In the Journals

Oral swabs show potential in TB detection

March 4, 2015
Use of oral swab specimens successfully identified up to 90% of confirmed tuberculosis cases, offering a viable alternative to sputum samples, according to the results…
Thomas Frieden, MD

Most pneumonia hospitalizations occur in children aged younger than 5 years

March 4, 2015
Seventy percent of pneumonia hospitalizations were among children aged younger than 5 years, according to study findings published in the New England Journal of
In the Journals

High-dose glucocorticoids linked to PCP infection in patients with autoimmune diseases

March 4, 2015
Patients with autoimmune diseases who developed Pneumocystis jirovecii pneumonia were more likely to have taken high doses of glucocorticoids, according to recently…
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Regimen Selection in HIV: Considering New Options to Optimize Outcomes

This activity is supported by an educational grant from Gilead Sciences Medical Affairs.

More than two decades into the antiretroviral therapy (ART) era, there are numerous options for HIV treatment. The goal…
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Video: Action needed to reduce CVD risks in HIV patients

February 28, 2015
SEATTLE — Steven Grinspoon, MD, of the Massachusetts General Hospital and Harvard Medical School, gives an…
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CME
Management of Pediatric Conjunctivitis and Otitis/Conjunctivitis Syndrome

Management of Pediatric Conjunctivitis and Otitis/Conjunctivitis Syndrome

This activity is supported by an educational grant from Alcon Research, LTD.

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