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Interferon-free regimen well tolerated in HIV/HCV coinfected patients

January 26, 2015

Treatment with an interferon-free regimen of sofosbuvir and ribavirin was well tolerated in patients with HIV/HCV coinfection and yielded improvements in patient-reported outcome scores that were comparable to those achieved by patients with HCV monoinfection, according to recent findings.

“Currently available interferon-free regimens have not only improved efficacy and safety for patients with chronic hepatitis C but also their patient-reported outcomes (PROs), such as health-related quality of life, fatigue, and work productivity,” Zobair M. Younossi, MD, vice president of research and chairman of the department of medicine at Inova Health System in Falls Church, Va., and colleagues wrote in the Journal of Infectious Diseases. “At the present time, it is unclear whether these PRO improvements can also be seen in HIV/HCV patients.”

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