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HSV-2 shedding increases after circumcision of HIV coinfected men

May 26, 2015

Penile shedding of herpes simplex virus type 2 appeared to be more prevalent among men coinfected with HIV in the weeks after circumcision, according to recently published data.

“Randomized trials have shown that male circumcision (MC) significantly decreases male heterosexual acquisition of HIV, HPV and HSV-2,” the researchers wrote. “[In a previous study,] both the number of HIV shedding events and the quantity of virus shed from the MC wound were significantly elevated in ART-naive HIV-positive men, in the first 3 weeks after MC. “It is unknown if MC also increases the frequency and intensity of HSV-2 shedding after surgery.”

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