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Piperacillin-tazobactam appeared inferior to carbapenems for ESBL bacteremia

January 28, 2015

Treatment with piperacillin-tazobactam appears inferior to carbapenems for treatment of extended-spectrum beta-lactamase–producing bacteria in the blood, researchers from Johns Hopkins University have learned.

“Our results suggest that carbapenems should be used as preferred therapy for patients suspected to have [extended-spectrum beta-lactamase (ESBL)] bacteremia,” they wrote in Clinical Infectious Diseases. “However, liberal use of carbapenems is not without consequence and can result in the emergence of resistance to this agent, severely limiting future treatment options.”

Margaret Chan

WHO resolves to improve response to public health emergencies

January 27, 2015
The WHO Executive Board unanimously adopted a resolution recently that would overhaul and strengthen the organization’s capacity to respond to disease outbreaks…

Victrelis expected to be discontinued by December

January 27, 2015
Merck expects to discontinue the manufacturing and distribution of its protease inhibitor Victrelis for the treatment of hepatitis C virus by December, according to a…
In the Journals

Various regimens effective in treating Chinese patients with HBV

January 27, 2015
In an open-label clinical trial, treatment-naive patients with hepatitis B virus infection showed similar sustained virologic response rates to four different treatment…
In the Journals

Long-acting ART most cost-effective for patients with multiple treatment failures

January 27, 2015
Long-acting ART could be beneficial for patients with HIV, particularly those with poor adherence to daily medication, according to researchers from Massachusetts…
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CME CNE CPE Video
Advances in Pharmacokinetic Enhancers in HIV Treatment: What You Need to Know to Optimize Outcomes

Advances in Pharmacokinetic Enhancers in HIV Treatment: What You Need to Know to Optimize Outcomes

This activity is supported by an educational grant from Bristol-Myers Squibb.

Protease inhibitors (PIs) have played an instrumental role in decreasing mortality andmorbidity among HIV-infected…
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Meeting News Coverage Video
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Student education, immunization requirements necessary to prevent outbreaks on college campuses

November 28, 2014
NEW YORK — James C. Turner, MD, executive director of the department of student health and the National Social…
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CME
HBV

Critical Issues in HBV
HBV Management in Complex Populations: Volume 1, Number 2

This activity is supported by an educational grant from Gilead Sciences Medical Affairs.

Hepatitis B virus (HBV) infection is a global epidemic with a worldwide burden. Physicians must address the importance…
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