September 1, 2015
Researchers from the United Kingdom have demonstrated the potential benefit of experimental antiviral agents as post-exposure prophylaxis for health care workers with possible exposure to Ebola virus, suggesting an urgent need for the development of international consensus guidelines regarding risk assessment and the use of these drugs.
In their study, published in the Lancet Infectious Diseases, the researchers developed an algorithm to evaluate exposure risk and devise suitable treatment strategies for health care workers (HCWs) with possible exposure to Ebola virus. The algorithm was used to assess eight HCWs from Sierra Leone who were evacuated to Royal Free Hospital in the U.K. after potential accidental exposure to the virus between January and March. The participants, aged 24 to 52 years, had no significant comorbid conditions and were provided direct patient care in Ebola treatment units.