Infectious Disease

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New antivirals viable PEP option in HCWs exposed to Ebola

September 1, 2015

Researchers from the United Kingdom have demonstrated the potential benefit of experimental antiviral agents as post-exposure prophylaxis for health care workers with possible exposure to Ebola virus, suggesting an urgent need for the development of international consensus guidelines regarding risk assessment and the use of these drugs.

In their study, published in the Lancet Infectious Diseases, the researchers developed an algorithm to evaluate exposure risk and devise suitable treatment strategies for health care workers (HCWs) with possible exposure to Ebola virus. The algorithm was used to assess eight HCWs from Sierra Leone who were evacuated to Royal Free Hospital in the U.K. after potential accidental exposure to the virus between January and March. The participants, aged 24 to 52 years, had no significant comorbid conditions and were provided direct patient care in Ebola treatment units.

FDA News

FDA cites safety issues, reclassifies C. difficile toxin gene amplification assays

September 1, 2015
The FDA has issued a final order and a special controls guideline to classify toxin gene amplification assays for the detection of Clostridium difficile as class II…
In the Journals

Seasonality in China linked to varicella, herpes zoster incidence

September 1, 2015
An increase in ambient temperature was associated with a decrease in outpatient visits for varicella and an increase in outpatient visits for herpes zoster, according to…
In the Journals

Active surveillance significantly reduces SSI rates after neurosurgery

September 1, 2015
The postoperative period for neurosurgery patients is associated with risk factors for surgical site infection that may go unnoticed, but active surveillance during this…

Pfizer continues study of Staphylococcus aureus vaccine for elective spinal fusion surgery

September 1, 2015
Pfizer Inc. announced the enrollment of the first patient in a Phase 2b clinical trial of its investigational Staphylococcus aureus multi-antigen vaccine in adults…
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CME
Infectious Disease Case Consults

The Patient with Conjunctivitis

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This CME activity will focus on the diagnosis and management of patients with conjunctivitis.
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At Issue Video
VIDEO: Cure is ‘next frontier’ of HIV

VIDEO: Cure is ‘next frontier’ of HIV

July 1, 2015
Timothy Brown – the Berlin patient – has led researchers to the next frontier of HIV research, according to…
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CME
Infectious Disease Case Consults

The Patient with Hepatitis C

No commercial support for this activity.

This CME activity will focus on the diagnosis and management of patients with hepatitis C.
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