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Two parasite types may worsen malaria in humans

May 29, 2015

Two genetically distinct Plasmodium knowlesi parasite subpopulations associated with different monkey host species in Malaysia are causing malaria in humans, raising the possibility that hybridization could lead to the creation of a more virulent strain with enhanced transmission, according to research published in PLoS Pathogens.

“We were very surprised to find that knowlesi malaria is really two separate zoonoses going on at the same time,” David J. Conway, PhD, professor of biology at the London School of Hygiene & Tropical Medicine, said in a press release. “There is a lot of genetic diversity within each of the parasite types, but the high level of divergence between them indicates they are probably different subspecies being transmitted separately within the same areas. If zoonotic transmission continues to be common, it becomes more likely that the two types may hybridize genetically, leading to new possibilities for parasite adaptation to humans or additional mosquito vectors.”

Meeting News Coverage

Infection treatment option proves effective in joint reconstruction cases

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PRAGUE — There was 78% eradication of infection in total joint replacement procedures at 3 years follow-up with a simple protocol used by orthopaedic surgeons at…
In the Journals

Higher viral load at admission predicts greater mortality in EVD patients

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FDA approvals

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Infectious Disease Case Consults

The Patient with Hepatitis C

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This CME activity will focus on the diagnosis and management of patients with hepatitis C.
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Meeting News Coverage Video
VIDEO: C-SURFER: Patients with kidney disease, HCV achieve high rates of SVR

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Management of Pediatric Conjunctivitis and Otitis/Conjunctivitis Syndrome

This activity is supported by an educational grant from Alcon Research, LTD.

Acute bacterial conjunctivitis affects approximately 1 of every 8 children each year, and 5 million cases occur in the…
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