Drug Metabolism/Pharmacology

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FDA approves Vantrela ER for severe pain

January 18, 2017

The FDA has approved Vantrela ER, an extended release tablet, for patients with severe pain that necessitates long-term, around-the-clock treatment, according to a press release from its manufacturer.

Teva Pharmaceuticals also stated that the prescribing information will include details on the drug’s abuse-deterrent properties, which may reduce IV, intranasal and oral misuse of the drug.

In the Journals

Combatting antimicrobial resistance critical for patients with cirrhosis

September 1, 2016
Worldwide public health concerns over antimicrobial resistance in pathogenic bacteria make it important to find solutions for preventing the spread of resistant…
In the Journals

TDF effective, safe in LAM-R chronic hepatitis B patients up to 5 years

August 29, 2016
Tenofovir disoproxil fumarate monotherapy was effective and well-tolerated in patients with lamivudine-resistant chronic hepatitis B up to 5 years, according to recent…
In the Journals

Ursodeoxycholic acid does not inhibit liver overgrowth

August 24, 2016
Ursodeoxycholic acid may not be a viable treatment option for some patients with polycystic liver disease, according to research recently published in the Journal of
CME

HCV Updates and Case Challenges for the Rapidly Changing Landscape

This activity is supported by an educational grant from Merck & Co., Inc.

In the past few years, significant progress has been made in the treatment of chronic hepatitis C virus (HCV). Highly…
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GI Bookshelf

Chapter 26: Functional Brain Imaging in GI Neurophysiology

From GI Motility Testing: A Laboratory and Office Handbook
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International Liver Congress

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Sofosbuvir, ribavirin therapy after liver transplant shows positive results for HCV patients

November 15, 2013
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FDA approves Vantrela ER for severe pain

January 18, 2017
The FDA has approved Vantrela ER, an extended release tablet, for patients with severe pain that necessitates long-term, around-the-clock treatment…

In the Journals

Combatting antimicrobial resistance critical for patients with cirrhosis

September 1, 2016
Worldwide public health concerns over antimicrobial resistance in pathogenic bacteria make it important to find solutions for preventing the spread…

In the Journals

TDF effective, safe in LAM-R chronic hepatitis B patients up to 5 years

August 29, 2016
Tenofovir disoproxil fumarate monotherapy was effective and well-tolerated in patients with lamivudine-resistant chronic hepatitis B up to 5 years…

In the Journals

Ursodeoxycholic acid does not inhibit liver overgrowth

August 24, 2016
Ursodeoxycholic acid may not be a viable treatment option for some patients with polycystic liver disease, according to research recently published…

In the Journals

DAA therapy may reduce number of LT candidates

August 18, 2016
Patients with hepatitis C virus, but without hepatocellular carcinoma treated with direct-acting antiviral agents saw lower MELD scores and improved…

CMS grants NTAP to Defitelio for treatment of hepatic VOD

August 9, 2016
Jazz Pharmaceuticals announced that CMS has granted a New Technology Add-on Payment for Defitelio, according to a press release. “CMS’…

In the Journals

DILI phenotypic features not associated with AIH alleles

August 5, 2016
According to an analysis published in Clinical Gastroenterology and Hepatology, phenotypic features of patients with drug-induced liver injury were…

In the Journals

Researchers develop liver model displaying metabolism zonation

July 27, 2016
According to data published in Scientific Reports, researchers at Massachusetts General Hospital developed a liver model displaying zonation of…

Galectin’s GR-MD-02 patent extended to Australia

July 21, 2016
Galectin Therapeutics announced it has received a Notice of Allowance from the Australian Government Patent Office. When issued, this patent will…

In the Journals

Organovo's 3-D bioprinted liver effectively models drug-induced injury

July 18, 2016
Organovo researchers developed a 3-D bioprinted liver that effectively modeled drug-induced injury and discerned highly related compounds with…

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