Chronic Hepatitis

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EMA panel recommends approval of Epclusa for all HCV genotypes

May 27, 2016

The European Committee for Medicinal Products for Human Use granted a positive opinion for Gilead Science’s Marketing Authorization Application for Epclusa for the treatment of all chronic hepatitis C genotypes, according to a press release from the manufacturer.

Epclusa (sofosbuvir/velpatasvir, Gilead Sciences) is an investigational, pangenotypic, once-daily tablet containing 400 mg of sofosbuvir and 100 mg of velpatasvir. The CHMP’s positive opinion was adopted following an accelerated review procedure and will now be reviewed by the European Commission, which has the authority to approve the drug for the European Union.

In the Journals

Nucleos(t)ide analogues reduce risk for recurrence in HBV-related HCC

May 25, 2016
Nucleos(t)ide analogues for hepatitis B virus infection decreased a patient’s risk for infection-related hepatocellular carcinoma after curative therapy with…
Meeting News Coverage

Systemic inflammatory response syndrome, sepsis contribute to mortality in alcoholic hepatitis

May 23, 2016
SAN DIEGO —  Data link systemic inflammatory response syndrome and sepsis with a nearly threefold increase in mortality among patients with alcoholic…
In the Journals

Off-therapy serum qHBsAg level can predict durability of Baraclude-treated HBV patients

May 23, 2016
Recent findings published in The American Journal of Gastroenterology showed that off-therapy serum quantitative hepatitis B surface antigen level can predict the…
CME

Rapid Response from Barcelona: New Data in HCV Treatment

This activity is supported by an educational grant from AbbVie and Merck & Co., Inc.

Chronic hepatitis C virus (HCV) infection is a leading cause of cirrhosis, end-stage liver disease, hepatocellular…
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Meeting News Coverage

Antiviral regimens produced high SVR rates in liver transplant recipients with recurring HCV

November 12, 2014
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Highlights from International Liver Congress

Highlights from International Liver Congress

Drug Pipeline

EMA panel recommends approval of Epclusa for all HCV genotypes

May 27, 2016
The European Committee for Medicinal Products for Human Use granted a positive opinion for Gilead Science’s Marketing Authorization Application…

In the Journals

Nucleos(t)ide analogues reduce risk for recurrence in HBV-related HCC

May 25, 2016
Nucleos(t)ide analogues for hepatitis B virus infection decreased a patient’s risk for infection-related hepatocellular carcinoma after…

Meeting News Coverage

Systemic inflammatory response syndrome, sepsis contribute to mortality in alcoholic hepatitis

May 23, 2016
SAN DIEGO —  Data link systemic inflammatory response syndrome and sepsis with a nearly threefold increase in mortality among patients…

In the Journals

Off-therapy serum qHBsAg level can predict durability of Baraclude-treated HBV patients

May 23, 2016
Recent findings published in The American Journal of Gastroenterology showed that off-therapy serum quantitative hepatitis B surface antigen level…

Meeting News CoverageVideo

VIDEO: Chronic liver disease has significant patient impact, economic burden

May 22, 2016
SAN DIEGO — In this exclusive video from DDW 2016, Zobair Younossi, MD, MPH, chairman of the department of medicine, Inova Fairfax Hospital…

Meeting News Coverage

Chronic liver disease represents 'excessive burden' for individuals, health care system

May 22, 2016
SAN DIEGO — Individuals with chronic liver disease were more likely to miss days of work and use health care services than those without…

HHS recognizes need for 'partnership' with hepatitis researchers

May 19, 2016
On National Viral Hepatitis Testing Day, the Department of Health and Human Services awarded 12 health care organizations for their continued work…

Hepatitis Testing Day: 4 studies show increased testing rates

May 19, 2016
It is estimated that one in 30 baby boomers have hepatitis C virus infection and one in 12 Asian Americans and Pacific Islanders have hepatitis B…

In the Journals

Indian Health Service increases HCV testing rate fourfold

May 18, 2016
The Indian Health Service expanded its hepatitis C virus infection testing to the birth cohort 1945 to 1965 after the CDC recommended a one-time HCV…

In the Journals

Statin use reduces risk for cirrhosis, decompensation in HBV

May 18, 2016
Statin use was associated with a decreased risk for developing cirrhosis and decompensation in Taiwanese patients with chronic hepatitis B virus…

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