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FDA approves Viekira Pak for treatment of HCV

December 19, 2014

The FDA today approved a treatment for patients with hepatitis C virus genotype 1 infection, including those with cirrhosis, according to a press release.

A combination of ombitasvir, paritaprevir and ritonavir tablets with dasabuvir tablets (Viekira Pak, AbbVie) is the fourth chronic HCV drug product the FDA has approved in the past 14 months, and the 11th drug to have previously received the FDA’s breakthrough therapy designation. It can be used with or without ribavirin, but is not recommended for patients with decompensated cirrhosis.

Clinical setbacks integral to long-term success in HCV treatment

December 19, 2014
In a new report, the Pharmaceutical Research and Manufacturers of America examined the successes and failures of hepatitis C virus infection research and therapies since…
Liver fibrosis, cirrhosis progressed faster in patients with HCV In the Journals

Liver fibrosis, cirrhosis progressed faster in patients with HCV

December 19, 2014
Veterans positive for hepatitis C virus infection were more likely to be diagnosed with liver fibrosis or cirrhosis after seroconversion compared with those who were…
In the Journals

HCV coinfection did not impair mental function in HIV patients

December 18, 2014
Neurocognitive performance did not appear to be associated with HCV coinfection among people with HIV, according to recently published data. David B. Clifford, MD
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HCV Consults: Volume 1, Number 3

HCV Consults: Volume 1, Number 3

This activity is supported by educational grants from AbbVie and Genentech, Inc.

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Early liver transplantation could improve survival rates for patients with alcoholic hepatitis

November 17, 2014
BOSTON — Ibrahim A. Hanouneh, MD, hepatologist at Cleveland Clinic, discussed results of a study that compared…
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HBV

Critical Issues in HBV
HBV Management in Complex Populations: Volume 1, Number 2

This activity is supported by an educational grant from Gilead Sciences Medical Affairs.

Hepatitis B virus (HBV) infection is a global epidemic with a worldwide burden. Physicians must address the importance…
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Edward Cox FDA approvals

FDA approves Viekira Pak for treatment of HCV

December 19, 2014
The FDA today approved a treatment for patients with hepatitis C virus genotype 1 infection, including those with cirrhosis, according to a press…

Clinical setbacks integral to long-term success in HCV treatment

December 19, 2014
In a new report, the Pharmaceutical Research and Manufacturers of America examined the successes and failures of hepatitis C virus infection research…
Liver fibrosis, cirrhosis progressed faster in patients with HCV In the Journals

Liver fibrosis, cirrhosis progressed faster in patients with HCV

December 19, 2014
Veterans positive for hepatitis C virus infection were more likely to be diagnosed with liver fibrosis or cirrhosis after seroconversion compared…
In the Journals

HCV coinfection did not impair mental function in HIV patients

December 18, 2014
Neurocognitive performance did not appear to be associated with HCV coinfection among people with HIV, according to recently published data. David
In the Journals

Rheumatic hand manifestations observed in chronic HCV

December 17, 2014
Hepatitis C virus infection prompted hand manifestations among Egyptian patients, according to study data.  “Patients infected with HCV…
In the Journals

Entecavir decreased HBV incidence, reactivation in patients undergoing R-CHOP for lymphoma

December 16, 2014
In a new phase 3 study, patients seropositive for the hepatitis B surface antigen with diffuse large B-cell lymphoma who underwent chemotherapy with…
In the Journals

Active HCV infection common among seropositive patients in sub-Saharan Africa

December 16, 2014
Viremic hepatitis C infection was frequent among individuals in sub-Saharan Africa who were serologically positive for the virus, according to new…
HCV, HIV/AIDS prevalent across certain regions of Massachusetts In the Journals

HCV, HIV/AIDS prevalent across certain regions of Massachusetts

December 12, 2014
In a new geospatial study, researchers identified multiple hot spots for hepatitis C virus infection and HIV/AIDS-related mortality across…

Added benefit of HCV drug unproven due to insufficient data

December 11, 2014
In a manufacturer dossier assessment, the Institute for Quality and Efficiency in Health Care in Germany was unable to deem daclatasvir more…
Simeprevir with PEG-IFN a-2a/ribavirin safely treated HCV In the Journals

Simeprevir with PEG-IFN a-2a/ribavirin safely treated HCV

December 11, 2014
In a new study, treatment with simeprevir and a combination of pegylated interferon alfa-2a and ribavirin yielded noninferior response rates to…
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