Autoimmune/Cholestatic/Biliary Diseases

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AIH, younger age increase risk for PSC recurrence in pediatric LT patients

May 10, 2017

CHICAGO — Researchers found that nearly a quarter of pediatric patients who underwent liver transplantation for primary sclerosing cholangitis had recurrence posttransplant, particularly patients who were younger or had autoimmune hepatitis, according to a presentation at Digestive Disease Week.

“Liver transplantation is the only therapy for primary sclerosing cholangitis. Most liver transplant outcomes for children are generally good. Pediatric onset PSC and PSC with autoimmune hepatitis overlap phenotype are quite rare. Furthermore, pediatric liver transplant for PSC is quite uncommon,” Fateh Bazerbachi, MD, from the Mayo Clinic, Rochester, Minnesota said. “Our study objective was to characterize the current PSC as [indication for] liver transplant using a large, multicenter international cohort of children with this disease.”

Meeting News

Prospective validation of ELF test confirms utility in PSC surveillance

May 8, 2017
CHICAGO — The Enhanced Liver Fibrosis test predicted increased risk of clinical events and progression to cirrhosis in patients with primary sclerosing…
Meeting News

EASL presents clinical guidelines for HBV, ALD, ALF, PBC, PSC

May 1, 2017
AMSTERDAM — At this year’s International Liver Congress, EASL presented new clinical practice guidelines for the diagnosis, management and treatment of…
Meeting News

EASL, ESGE publish clinical guide on the role of endoscopy in PSC

April 28, 2017
AMSTERDAM — The European Association for the Study of the Liver and the European Society of Gastrointestinal Endoscopy released their new guideline on the role of…
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VIDEO: Intercept Pharmaceuticals VP discusses EASL guidelines for PBC

April 26, 2017
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Meeting News

AIH, younger age increase risk for PSC recurrence in pediatric LT patients

May 10, 2017
CHICAGO — Researchers found that nearly a quarter of pediatric patients who underwent liver transplantation for primary sclerosing cholangitis…

Meeting News

Prospective validation of ELF test confirms utility in PSC surveillance

May 8, 2017
CHICAGO — The Enhanced Liver Fibrosis test predicted increased risk of clinical events and progression to cirrhosis in patients with primary…

Meeting News

EASL presents clinical guidelines for HBV, ALD, ALF, PBC, PSC

May 1, 2017
AMSTERDAM — At this year’s International Liver Congress, EASL presented new clinical practice guidelines for the diagnosis, management…

Meeting News

EASL, ESGE publish clinical guide on the role of endoscopy in PSC

April 28, 2017
AMSTERDAM — The European Association for the Study of the Liver and the European Society of Gastrointestinal Endoscopy released their new…

Meeting News

EASL releases guidelines for the diagnosis, management of PBC

April 26, 2017
AMSTERDAM — The European Association for the Study of the Liver presented its new Clinical Practice Guideline for the diagnosis and management…

Meeting NewsVideo

VIDEO: Intercept Pharmaceuticals VP discusses EASL guidelines for PBC

April 26, 2017
AMSTERDAM — In this exclusive video from International Liver Congress, Rick Lones, vice president, head of medical affairs for Europe, Canada…

Meeting NewsVideo

VIDEO: Physician discusses importance of Ocaliva license in Europe

April 25, 2017
AMSTERDAM — In this exclusive video from International Liver Congress, Rick Lones, vice president, head of medical affairs for Europe, Canada…

Meeting News

Rituximab not effective for treating fatigue in PBC

April 24, 2017
AMSTERDAM — Rituximab was not effective in treating fatigue in unselected patients with primary biliary cholangitis despite metabolic…

Meeting News

Ileal bile acid transporter inhibition promising for cholestatic liver disease

April 22, 2017
AMSTERDAM — A novel approach for cholestatic pruritus, ileal bile acid transporter inhibition, was associated with improvement in pruritus in…

Meeting News

Bezafibrate shows efficacy used in combination with UDCA for PBC

April 22, 2017
AMSTERDAM — Bezafibrate induced an additional biochemical response in patients with primary biliary cholangitis, improving pruritus and other…

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