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Daratumumab-based triplet highly effective in relapsed, refractory myeloma

August 24, 2016

The addition of daratumumab to bortezomib and dexamethasone significantly improved PFS in patients with relapsed and refractory multiple myeloma, according to phase 3 trial results published in The New England Journal of Medicine.

However, more patients treated with the triplet regimen experienced infusion-related reactions, thrombocytopenia and neutropenia than patients treated with bortezomib (Velcade; Takeda/Millennium) and dexamethasone alone.

In the Journals

Advanced cutaneous head and neck melanoma more often diagnosed on posterior locations

August 24, 2016
Advanced cutaneous head and neck melanomas were diagnosed more often on the scalp or back of the neck compared with anterior locations, according to recently published…
In the Journals Plus

Eight additional cancer types associated with excess body fatness

August 24, 2016
The WHO’s International Agency for Research on Cancer working group identified an additional eight types of cancer associated with excess body fatness, including…
In the Journals

Breast cancer risk, breast density useful in guiding mammogram frequency

August 24, 2016
Tailoring mammography screening intervals to each patient will help in maximizing benefits and minimizing harms, according to findings published in the Annals of

Bayer awards grants for research into hemophilia, bleeding disorders

August 24, 2016
Bayer awarded six grants to U.S. clinicians and investigators for research and educational initiatives in hemophilia and related bleeding disorders. The recipients are…
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Updates from Vienna 2015 – Highlights in Hematologic Malignancies

This activity is supported by an educational grant from Genentech, Inc.

The management of patients with hematologic malignancies—from diagnosis to treatment decisions—can represent a…
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At Issue

VIDEO: Immune checkpoint inhibitors show promise in metastatic, triple-negative breast cancer

August 9, 2016
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Discoveries from ASCO 2016: Breast Cancer

Discoveries from ASCO 2016: Breast Cancer

CME Video

Optimizing the Management of Metastatic Melanoma: Clinical Insights for Selecting First-line Therapy

This activity is supported by an independent educational grant from Merck & Co., Inc.

The incidence of melanoma is continuing to increase worldwide. In recent years, the treatment landscape for this…
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