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Genomic data may better classify lower-grade glioma than histology

June 30, 2015

Read the Perspective from Stephanie Weiss, MD, MD

IDH, 1p/19q and TP53 status more accurately represented three molecular classes of lower-grade gliomas than histologic class, according to study results.

Lower-grade gliomas with an IDH mutation also had codeletion of chromosome arms 1p and 19q or a TP53 mutation, whereas lower-grade gliomas without IDH mutations demonstrated molecular and clinical similarity to glioblastoma, results showed.

In the Journals

Incidence of high-grade cervical lesions has declined due to screening, vaccination

June 30, 2015
The incidence of high-grade cervical lesions has decreased in young women in the U.S. since the approval of HPV vaccines, according to study results.However, this…
No association found between secondary osteosarcoma, chondroblastic subtype In the Journals

No association found between secondary osteosarcoma, chondroblastic subtype

June 30, 2015
No association was found between secondary osteosarcoma and chondroblastic subtype, according to study results.Researchers performed a retrospective chart review and…
In the Journals

Online searches for melanoma, skin cancer increase in summer

June 30, 2015
Online searches for the terms melanoma and skin cancer increased during each summer over a 5-year period, according to a recently published report.Researchers used…
In the Journals

HSCT improves survival for older patients with multiple myeloma

June 30, 2015
Hematopoietic stem cell transplantation improved OS for elderly patients with multiple myeloma in the real-world setting, according to results of a SEER…
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CME
Hematology Oncology Case Consults

Diagnosis and Management of Hemophilia

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This CME activity will focus on the diagnosis and management of the patient with hemophilia supplemented with a case…
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Meeting News Coverage Video
VIDEO: Complete lymph node dissection does not improve outcomes in SLNB-positive melanoma

VIDEO: Complete lymph node dissection does not improve outcomes in SLNB-positive melanoma

June 19, 2015
CHICAGO — Vernon K. Sondak, MD, chair of the department of cutaneous oncology at Moffitt Cancer Center and a…
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CME
Hematology Oncology Case Consults

The Patient with Chronic Lymphocytic Leukemia

No commercial support for this activity.

This CME activity will focus on the diagnosis and management of patients with chronic lymphocytic leukemia.
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