Top Story

FDA grants grants breakthrough therapy designation to JCAR015 for ALL

November 24, 2014

The FDA granted breakthrough therapy designation to JCAR015, a chimeric antigen receptor-modified T-cell therapy candidate, for the treatment of patients with relapsed/refractory B-cell acute lymphoblastic leukemia who have not received prior therapy, according to the manufacturer.

Originally developed for treatment of patients with aggressive B-cell non-Hodgkin’s lymphoma, JCAR015 (Juno Therapeutics) is designed to target CD19, identified on most B-cell malignancies, including various subtypes of NHL and ALL.

Meeting News Coverage

Postoperative radiation extended survival in resected NSCLC

November 24, 2014
Postoperative radiotherapy improved survival by approximately 4 months in patients with resected non–small cell lung cancer with pathologically involved N2 lymph nodes…
Institution Notes

UC Davis appoints chair of department of public health sciences

November 23, 2014
Brad Pollock, PhD, MPH, has been named chair of the department of public health sciences at UC Davis School of Medicine. Pollock, whose research focuses on the incidence…
Institution Notes

NYU Langone names cancer center director

November 22, 2014
Benjamin G. Neel, MD, PhD, has been named director of the Laura and Isaac Perlmutter Cancer Center at NYU Langone Medical Center.The appointment will be effective Jan. 1.
Edith Perez, MD In the Journals

Trastuzumab plus adjuvant chemotherapy improved OS DFS in HER 2 positive breast cancer

November 21, 2014
The addition of trastuzumab to adjuvant chemotherapy conferred “substantial and durable improvement in survival” among women with early-stage…
More News Headlines »
Stem Cell Transplant for AAMDS

Treatment Decision-Making through the Spectrum of MDS: Case 3 Stem Cell Transplant for MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain to…
More »
Meeting News Coverage Video
thumbnail for video 3886443649001

Risk stratification guidelines help determine treatment for thyroid cancer

November 11, 2014
Fabian Pitoia, MD,  head of the thyroid section of the division of endocrinology at the Hospital de Clinicas of…
More »
Hot melanoma

Targeted Therapy and Immunotherapy in the Management of Metastatic Melanoma: 2014 Updates - Monograph

Melanoma remains a challenging condition for clinicians. An array of targeted therapies and immunotherapy are in…
More »