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Trastuzumab plus adjuvant chemotherapy improved OS DFS in HER 2 positive breast cancer

November 21, 2014

The addition of trastuzumab to adjuvant chemotherapy conferred “substantial and durable improvement in survival” among women with early-stage, HER-2–positive breast cancer, according to a joint analysis of long-term results from randomized two trials.

“This study reflects that excellent science in collaboration between NCI-sponsored cancer cooperative groups and our patients can clearly help improve standards of care,” Edith A. Perez, MD, director of the breast cancer program at Mayo Clinic in Jacksonville, Fla., and a HemOnc Today Editorial Board member, told HemOnc Today. “Some specifics included a very low rate of local recurrence and serious cardiac side effects, even though all patients received anthracyclines prior to paclitaxel–trastuzumab. This regimen is a well-established standard of care regimen for eligible patients.”

In the Journals

Endoscopists regularly overuse colonoscopy screenings for colorectal cancer

November 21, 2014
Endoscopists commonly recommended more frequent colonoscopy screenings and surveillance for colorectal cancer than current recommended guidelines, according to study…
Meeting News Coverage

American Indians, Alaskan Natives experienced shorter cancer survival, even with equal access to care

November 21, 2014
Cancer survivors of American Indian or Alaskan Native descent demonstrated poorer rates of 5- and 10-year cancer survival than non-Hispanic whites even when they had…
Jeffrey Kullgren, MD In the Journals

Lottery incentive improved fecal occult blood test completion rates

November 21, 2014
Among several different financial incentives tested, a lottery-style cash reward increased rates of completion of fecal occult blood tests for colon cancer screening…
Meeting News Coverage

Preoperative transcutaneous oximetry predicted complications in sarcoma radiation

November 21, 2014
The use of preoperative transcutaneous oximetry may be useful in predicting wound-healing complications in patients undergoing surgery for soft tissue sarcomas after…
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Treatment Decision-Making through the Spectrum of MDS: Case 1 Low Risk MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain MDS…
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Risk stratification guidelines help determine treatment for thyroid cancer

November 11, 2014
Fabian Pitoia, MD,  head of the thyroid section of the division of endocrinology at the Hospital de Clinicas of…
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Targeted Therapy and Immunotherapy in the Management of Metastatic Melanoma: 2014 Updates - Monograph

Melanoma remains a challenging condition for clinicians. An array of targeted therapies and immunotherapy are in…
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